Breast cancer and circadian disruption from electric lighting in the modern world

RG Stevens, GC Brainard, DE Blask… - CA: a cancer journal …, 2014 - Wiley Online Library
Breast cancer is the leading cause of cancer death among women worldwide, and there is
only a limited explanation of why. Risk is highest in the most industrialized countries but also …

Circadian molecular clocks and cancer

FC Kelleher, A Rao, A Maguire - Cancer letters, 2014 - Elsevier
Physiological processes such as the sleep-wake cycle, metabolism and hormone secretion
are controlled by a circadian rhythm adapted to 24 h day-night periodicity. This circadian …

How sleep and wakefulness influence circadian rhythmicity: effects of insufficient and mistimed sleep on the animal and human transcriptome

SN Archer, H Oster - Journal of sleep research, 2015 - Wiley Online Library
The mammalian circadian system is a multi‐oscillator, hierarchically organised system
where a central pacemaker synchronises behavioural, physiological and gene expression …

Night shift work, chronotype and prostate cancer risk in the MCC‐S pain case‐control study

K Papantoniou, G Castaño‐Vinyals… - … journal of cancer, 2015 - Wiley Online Library
Night shift work has been classified as a probable human carcinogen based on
experimental studies and limited human evidence on breast cancer. Evidence on other …

The impact of shiftwork on health: a literature review

A Matheson, L O'Brien, JA Reid - Journal of Clinical Nursing, 2014 - Wiley Online Library
Aims and objectives To identify the impact of shiftwork on individuals and their lives and to
discuss the implications this has for nurses and nursing. Background The context of …

Clocking cancer: the circadian clock as a target in cancer therapy

F Battaglin, P Chan, Y Pan, S Soni, M Qu, ER Spiller… - Oncogene, 2021 - nature.com
Disruption of the cellular pathway modulating endogenous 24-h rhythms, referred to as “the
circadian clock”, has been recently proven to be associated with cancer risk, development …

Nocturnal light pollution and underexposure to daytime sunlight: Complementary mechanisms of circadian disruption and related diseases

MH Smolensky, LL Sackett-Lundeen… - Chronobiology …, 2015 - Taylor & Francis
Routine exposure to artificial light at night (ALAN) in work, home, and community settings is
linked with increased risk of breast and prostate cancer (BC, PC) in normally sighted women …

Shiftwork‐mediated disruptions of circadian rhythms and sleep homeostasis cause serious health problems

S Khan, P Duan, L Yao, H Hou - International journal of …, 2018 - Wiley Online Library
Shiftwork became common during the last few decades with the growing demands of human
life. Despite the social inactivity and irregularity in habits, working in continuous irregular …

Does night-shift work increase the risk of prostate cancer? A systematic review and meta-analysis

D Rao, H Yu, Y Bai, X Zheng, L **e - OncoTargets and therapy, 2015 - Taylor & Francis
Background Night-shift work is suggested to be associated with an increased risk of breast
cancer, but its association with prostate cancer is still controversial. We examined this …

[HTML][HTML] The circadian clock gene, Bmal1, regulates intestinal stem cell signaling and represses tumor initiation

K Stokes, M Nunes, C Trombley, DEFL Flôres… - Cellular and molecular …, 2021 - Elsevier
Background & Aims Circadian rhythms are daily physiological oscillations driven by the
circadian clock: a 24-hour transcriptional timekeeper that regulates hormones, inflammation …