Vitamin D and its' metabolites are a crucial part of the endocrine system that controls whole
body calcium homeostasis. The goal of this hormonal control is to regulate serum calcium …

Calcium balance is essential for a multitude of physiological processes, ranging from cell
signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a …

Rickets and hyperparathyroidism caused by a defective vitamin D receptor (VDR) can be
prevented in humans and animals by high calcium intake, suggesting that intestinal calcium …

The biologically active metabolite of vitamin D (cholecalciferol), ie 1, 25-dihydroxyvitamin D3
[1, 25 (OH) 2D3], is a secosteroid hormone whose mode of action involves stereospecific …

Adequate blood calcium concentrations are vital for the normal function of mammals.
Mechanisms for maintaining normal blood calcium function adequately most of the time; …

Hypocalcemia based on serum tCa is a relatively common laboratory abnormality and was
observed in 13.5% of serum biochemical profiles of dogs in one clinical study. 111 Based on …

Microarray technology has been used to discover 1, 25-dihydroxyvitamin D3 (1, 25-(OH)
2D3) induced gene expression changes in rat small intestine in vivo. Here, we report gene …

1, 25-Dihydroxyvitamin D 3 (1, 25 (OH) 2 D 3) plays an integral role in calcium homeostasis
in higher organisms through its actions in the intestine, kidney, and skeleton. Interestingly …

The central role of vitamin D in calcium homeostasis is to increase calcium absorption from
the intestine. This article describes the early work that served as the foundation for the initial …

Egg laying and shell calcification impose severe extra demands on ionic calcium (Ca2+)
homeostasis; especially in birds characterized by their long clutches (series of eggs laid …