Nanomedicine for the detection and treatment of ocular bacterial infections

X Huang, L Li, Z Chen, H Yu, X You, N Kong… - Advanced …, 2023 - Wiley Online Library
Ocular bacterial infection is a prevalent cause of blindness worldwide, with substantial
consequences for normal human life. Traditional treatments for ocular bacterial infections …

Theranostic platforms for specific discrimination and selective killing of bacteria

X Ye, T Feng, L Li, T Wang, P Li, W Huang - Acta Biomaterialia, 2021 - Elsevier
Bacterial infections are serious threats to public health due to lack of advanced techniques
to rapidly and accurately diagnose these infections in clinics. Although bacterial infections …

Delivery of antisense oligonucleotides using multi-layer coated gold nanoparticles to methicillin-resistant S. aureus for combinatorial treatment

MJ Beha, JS Ryu, YS Kim, HJ Chung - Materials Science and Engineering …, 2021 - Elsevier
The spread of multidrug-resistant (MDR) bacterial infections has become a serious global
threat. We introduce multi-layer coated gold nanoparticles (MLGNPs) delivering antisense …

Rapid and selective electrochemical sensing of bacterial pneumonia in human sputum based on conductive polymer dot electrodes

HJ Jo, JS Ryu, AI Robby, YS Kim, HJ Chung… - Sensors and Actuators B …, 2022 - Elsevier
A rapid wireless electrochemical biosensor that can discriminate between gram-negative
and gram-positive bacteria is designed for the selective detection of pneumonia pathogens …

A lateral flow assay for nucleic acid detection based on rolling circle amplification using capture ligand-modified oligonucleotides

HN Lee, J Lee, YK Kang, JH Lee, S Yang, HJ Chung - BioChip Journal, 2022 - Springer
We introduce a lateral flow assay (LFA) integrated with a modified isothermal nucleic acid
amplification procedure for rapid and simple genetic testing. Padlock probes specific for the …

Polydopamine sensors of bacterial hypoxia via fluorescence coupling

JH Lee, JS Ryu, YK Kang, H Lee… - Advanced Functional …, 2021 - Wiley Online Library
Biological catecholamines play critical physiological roles in various parts of the human
body, namely, the skin and brain. In the skin, an oxygen‐contacting and oxygen‐abundant …

Recent progress in identifying bacteria with fluorescent probes

Y Ji, G Li, J Wang, C Piao, X Zhou - Molecules, 2022 - mdpi.com
The development of new techniques to rapidly and accurately detect bacteria has drawn
continuous attention due to the potential threats posed by bacteria to human health and …

Functionalization of thermoswitchable liposomes for rapid detection of Gram-negative bacteria

JR Tan, B **ng, CLK Lee - Sensors and Actuators B: Chemical, 2022 - Elsevier
Biosensors for rapid and sensitive detection of pathogens play a crucial role in healthcare
and food safety. Despite the development of numerous sensing devices, it remains a …