Mechanisms and functions of long non-coding RNAs at multiple regulatory levels
X Zhang, W Wang, W Zhu, J Dong, Y Cheng… - International journal of …, 2019 - mdpi.com
Long non-coding (lnc) RNAs are non-coding RNAs longer than 200 nt. lncRNAs primarily
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …
interact with mRNA, DNA, protein, and miRNA and consequently regulate gene expression …
The multidimensional mechanisms of long noncoding RNA function
A major shift in our understanding of genome regulation has emerged recently. It is now
apparent that the majority of cellular transcripts do not code for proteins, and many of them …
apparent that the majority of cellular transcripts do not code for proteins, and many of them …
Mechanisms of long noncoding RNA function in development and disease
SU Schmitz, P Grote, BG Herrmann - Cellular and molecular life sciences, 2016 - Springer
Since decades it has been known that non-protein-coding RNAs have important cellular
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
functions. Deep sequencing recently facilitated the discovery of thousands of novel …
Genomic imprinting disorders: lessons on how genome, epigenome and environment interact
Genomic imprinting, the monoallelic and parent-of-origin-dependent expression of a subset
of genes, is required for normal development, and its disruption leads to human disease …
of genes, is required for normal development, and its disruption leads to human disease …
The long noncoding RNA Malat1: Its physiological and pathophysiological functions
Recent studies suggest that in humans, DNA sequences responsible for protein coding
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
regions comprise only 2% of the total genome. The rest of the transcripts result in RNA …
Long non-coding RNA: its evolutionary relics and biological implications in mammals: a review
The central dogma of gene expression propounds that DNA is transcribed to mRNA and
finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …
finally gets translated into protein. Only 2–3% of the genomic DNA is transcribed to protein …
Long noncoding RNA: genome organization and mechanism of action
For the last four decades, we have known that noncoding RNAs maintain critical
housekee** functions such as transcription, RNA processing, and translation. However, in …
housekee** functions such as transcription, RNA processing, and translation. However, in …
Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility
Abstract Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp
and are known to regulate a host of crucial cellular processes like proliferation …
and are known to regulate a host of crucial cellular processes like proliferation …
Long non-coding RNAs and cervical cancer
Cervical cancer is determined as the second highest number of deaths factor in female
cancers. Here is a need to find new biomarkers for detection and preliminary prognosis …
cancers. Here is a need to find new biomarkers for detection and preliminary prognosis …
[BOOK][B] RNA, the epicenter of genetic information
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …