Simple Summary A brief description of the methodologies to simulate ionizing radiation
transport in biologically relevant matter is presented. Emphasis is given to the physical …

Ionizing radiation is a common tool in medical procedures. Monte Carlo (MC) techniques are
widely used when dosimetry is the matter of investigation. The scientific community has …

The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Ionising radiation induced DNA damage and subsequent biological responses to it depend
on the radiation's track-structure and its energy loss distribution pattern. To investigate the …

Purpose The simulation of individual particle tracks and the chemical stage following water
radiolysis in biological tissue is an effective means of improving our knowledge of the …

Purpose The scientific community shows great interest in the study of DNA damage
induction, DNA damage repair, and the biological effects on cells and cellular systems after …

The chemical stage of the Monte Carlo track-structure simulation code Geant4-DNA has
been revised and validated. The root-mean-square (RMS) empirical parameter that dictates …

The cellular response to ionizing radiation continues to be of significant research interest in
cancer radiotherapy, and DNA is recognized as the critical target for most of the biologic …

The relative biological effectiveness (RBE) calculations used during the planning of ion
therapy treatments are generally based on the microdosimetric kinetic model (MKM) and the …

Simple Summary DNA damage caused by ionizing radiation in a human fibroblast cell
evaluated by the Geant4-DNA Monte Carlo toolkit is presented. A validation study using a …