The role of Pannexin (PANX) channels during collective and single cell migration is
increasingly recognized. Amongst many functions that are relevant to cell migration, here we …

Single cells migrate in a myriad of physiological contexts, such as tissue patrolling by
immune cells, and during neurogenesis and tissue remodeling, as well as in metastasis, the …

To reach inflamed tissues from the circulation, neutrophils must overcome physical
constraints imposed by the tissue architecture, such as the endothelial barrier or the three …

Niemann-Pick type A (NPA) disease is a fatal lysosomal neurodegenerative disorder caused
by the deficiency in acid sphingomyelinase (ASM) activity. NPA patients present severe and …

Upon infection, mature dendritic cells (mDCs) migrate from peripheral tissue to lymph nodes
(LNs) to activate T lymphocytes and initiate the adaptive immune response. This fast and …

Dendritic cells (DCs), which are immune sentinels in the peripheral tissues, play a number of
roles, including patrolling for pathogens, internalising antigens, transporting antigens to the …

Background Rubella virus–induced granulomas have been described in patients with
various inborn errors of immunity. Most defects impair T-cell immunity, suggesting a critical …

This article is part of the Dendritic Cell Guidelines article series, which provides a collection
of state‐of‐the‐art protocols for the preparation, phenotype analysis by flow cytometry …

Orchestrated recruitment of neutrophils to inflamed tissue is essential during the initiation of
inflammation. Inflamed areas are usually hypoxic, and adaptation to reduced oxygen …

Highlights•Calcium ions (Ca 2+) control migration of dendritic cells.•Ca 2+ channels are
differentially associated to distinct stages of dendritic cell migration.•Non-selective Ca 2+ …