[HTML][HTML] An update on β-sitosterol: A potential herbal nutraceutical for diabetic management

S Babu, S Jayaraman - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Phytosterols are bioactive compounds that are naturally present in plant cell membranes
with chemical structure similar to the mammalian cell-derived cholesterol. They are highly …

[HTML][HTML] A comprehensive review on phytochemistry, bioactivities, toxicity studies, and clinical studies on Ficus carica Linn. leaves

Z Li, Y Yang, M Liu, C Zhang, J Shao, X Hou… - Biomedicine & …, 2021 - Elsevier
The leaves of Ficus carica Linn.(FC) have been widely used for medicine purposes since
ancient times, and its decoction is consumed as tea. Many scientific papers have been …

Glyphosate potentiates insulin resistance in skeletal muscle through the modulation of IRS-1/PI3K/Akt mediated mechanisms: an in vivo and in silico analysis

S Jayaraman, K Krishnamoorthy, M Prasad… - International Journal of …, 2023 - Elsevier
Herbicides have been linked to a higher risk of develo** diabetes. Certain herbicides also
operate as environmental toxins. Glyphosate is a popular and extremely effective herbicide …

Piperine modulates IR/Akt/GLUT4 pathways to mitigate insulin resistance: Evidence from animal and computational studies

M Prasad, S Jayaraman, SR Natarajan… - International Journal of …, 2023 - Elsevier
The global prevalence of diabetes mellitus is rising, especially in India. Medicinal herbs,
whether used alone or in combination with conventional medicines, have shown promise in …

A comprehensive review on therapeutic perspectives of phytosterols in insulin resistance: a mechanistic approach

M Prasad, S Jayaraman, MA Eladl, M El-Sherbiny… - Molecules, 2022 - mdpi.com
Natural products in the form of functional foods have become increasingly popular due to
their protective effects against life-threatening diseases, low risk of adverse effects …

β-Sitosterol attenuates dexamethasone-induced muscle atrophy via regulating FoxO1-dependent signaling in C2C12 cell and mice model

YS Hah, WK Lee, S Lee, EJ Kim, JH Lee, SJ Lee, YH Ji… - Nutrients, 2022 - mdpi.com
Sarcopenia refers to a decline in muscle mass and strength with age, causing significant
impairment in the ability to carry out normal daily functions and increased risk of falls and …

Gut microbiome dysregulation drives bone damage in broiler tibial dyschondroplasia by disrupting glucose homeostasis

T Xu, P Chen, C Zhang, A Shaukat, L Lin… - npj Biofilms and …, 2023 - nature.com
Tibial dyschondroplasia (TD) with multiple incentives is a metabolic skeletal disease that
occurs in fast-growing broilers. Perturbations in the gut microbiota (GM) have been shown to …

Cancer chemotherapy via natural bioactive compounds

K Pathak, MP Pathak, R Saikia, U Gogoi… - Current Drug …, 2022 - ingentaconnect.com
Background: Cancer-induced mortality is increasingly prevalent globally, which skyrocketed
the necessity to discover new/novel, safe and effective anticancer drugs. Cancer is …

High-intensity interval training, caloric restriction, or their combination have beneficial effects on metabolically acquired peripheral neuropathy

SA Eid, SE Elzinga, B Kim, AE Rumora, JM Hayes… - Diabetes, 2024 - diabetesjournals.org
Peripheral neuropathy (PN) is a prevalent and debilitating complication of obesity,
prediabetes, and type 2 diabetes, which remains poorly understood and lacks disease …

β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis

D Zhang, F Ge, J Ji, YJ Li, FR Zhang… - Frontiers in …, 2023 - frontiersin.org
Background: Inflammation-related NLRP3/Caspase-1/GSDMD-mediated pyroptosis is
involved in the progression of ulcerative colitis (UC). β-sitosterol (SIT) was reported to have …