For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …

Background: Thiazole is a good nucleus owing to its various pharmaceutical applications.
Thiazole containing compounds (thiazoles) have shown various biological activities like …

The synthesis and X-ray characterization of three new 4, 5-dihydropyrazolylthiazole–
coumarin hybrids (1–3) are reported herein, namely 3-(2-(3, 5-bis (4-chlorophenyl)-4, 5 …

Schiff bases represent a valuable class of organic compounds, synthesized via
condensation of primary amines with ketones or aldehydes. They are renowned for …

The pivotal involvement of reverse transcriptase activity in the pathogenesis of the
progressive HIV virus has stimulated gradual advancements in drug discovery initiatives …

Fragment merging approach was applied for the design of thiazole/thiazolidinone clubbed
pyrazoline derivatives 5a-e, 6a-c, 7 and 10a-d as dual COX-2 and 5-LOX inhibitors …

Human immunodeficiency virus (HIV) especially HIV-1 infection and its progression to
acquired immune deficiency syndrome (AIDS) remains a significant global health challenge …

The ever-increasing environmental pollution and its health concerns appeal replacement of
conventional organic synthesis with green synthetic methodology. This review presented …

The synthesis and X-ray characterization of 1-(2-(3-(4-bromophenyl)-5-(4-methoxyphenyl)-4,
5-dihydro-1H-pyrazol-1-yl)-4-methylthiazol-5-yl) ethanone (7), ethyl 2-(5-(4-bromophenyl)-3 …

In this manuscript, we synthesized a novel ethyl 2-(5-(4-methoxyphenyl)-3-phenyl-4, 5-
dihydro-1H-pyrazol-1-yl) thiazole-4-carboxylate (5) from the reaction acetophenone with 3 …