The Diels–Alder reaction in total synthesis

KC Nicolaou, SA Snyder, T Montagnon… - Angewandte Chemie …, 2002 - Wiley Online Library
Abstract The Diels–Alder reaction has both enabled and shaped the art and science of total
synthesis over the last few decades to an extent which, arguably, has yet to be eclipsed by …

Transition metal-mediated cycloaddition reactions

M Lautens, W Klute, W Tam - Chemical reviews, 1996 - ACS Publications
The discovery and development of new chemical reactions is a major focus of research
activity in organic chemistry. The chemical synthesis of molecules provided by Nature has …

New strategies for organic catalysis: the first highly enantioselective organocatalytic Diels− Alder reaction

KA Ahrendt, CJ Borths… - Journal of the American …, 2000 - ACS Publications
Over the past 30 years, enantioselective catalysis has become one of the most important
frontiers in exploratory organic synthetic research. During this time, remarkable advances …

Catalytic enantioselective Diels–Alder reactions: methods, mechanistic fundamentals, pathways, and applications

EJ Corey - Angewandte Chemie International Edition, 2002 - Wiley Online Library
Conference of 2001, and describes research by our group on the development and
understanding of enantioselective versions of the Diels±Alder reactions. The elements of …

The catalytic enantioselective construction of molecules with quaternary carbon stereocenters

EJ Corey, A Guzman‐Perez - … Chemie International Edition, 1998 - Wiley Online Library
A long‐standing challenge to synthesis can now be met through the use of new and
powerful catalytic asymmetric reactions for the assembly of complex chiral molecules with …

Chemistry and biology of mycotoxins and related fungal metabolites

S Bräse, A Encinas, J Keck, CF Nising - Chemical reviews, 2009 - ACS Publications
Nature produces a variety of different species, prokaryotes and eukaryotes. Among them,
fungi play a very important, but yet mostly unexplored role. Their widespread occurrence on …

Catalytic enantioselective construction of all-carbon quaternary stereocenters

BM Trost, C Jiang - Synthesis, 2006 - thieme-connect.com
Catalytic enantioselective construction of all-carbon quaternary stereocenters, ie carbon
atoms bearing four different carbon substituents, poses a particular challenge in organic …

Catalytic asymmetric hetero‐Diels–Alder reactions of carbonyl compounds and imines

KA Jørgensen - Angewandte Chemie International Edition, 2000 - Wiley Online Library
Asymmetric catalysis is a challenge for chemists: How can we design catalysts to achieve
the goal of forming optically active compounds? This review provides the reader with an …

A novel chiral super-Lewis acidic catalyst for enantioselective synthesis

Y Hayashi, JJ Rohde, EJ Corey - Journal of the American …, 1996 - ACS Publications
The exceptional power of the Diels-Alder reaction in the synthesis of complex organic
molecules has been greatly enhanced by newly developed enantioselective versions …

Asymmetric catalysis: an enabling science

BM Trost - Proceedings of the National Academy of Sciences, 2004 - pnas.org
Chirality of organic molecules plays an enormous role in areas ranging from medicine to
material science, yet the synthesis of such entities in one enantiomeric form is one of the …