Brain connectivity in neurodegenerative diseases—from phenotype to proteinopathy
Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …
Cognitive decline in Parkinson's disease: the complex picture
Mild cognitive impairment (PD-MCI) and dementia (PDD) are among the most frequent non-
motor symptoms in Parkinson's disease (PD). PD-MCI is six times more likely than age …
motor symptoms in Parkinson's disease (PD). PD-MCI is six times more likely than age …
Multimodal neuroimaging in post-COVID syndrome and correlation with cognition
M Díez-Cirarda, M Yus, N Gómez-Ruiz, C Polidura… - Brain, 2023 - academic.oup.com
Brain changes have been reported in the first weeks after SARS-CoV-2 infection. However,
limited literature exists about brain alterations in post-COVID syndrome, a condition …
limited literature exists about brain alterations in post-COVID syndrome, a condition …
Brain iron deposition is linked with cognitive severity in Parkinson's disease
Background Dementia is common in Parkinson's disease (PD) but measures that track
cognitive change in PD are lacking. Brain tissue iron accumulates with age and co-localises …
cognitive change in PD are lacking. Brain tissue iron accumulates with age and co-localises …
Biomarkers for dementia and mild cognitive impairment in Parkinson's disease
M Delgado‐Alvarado, B Gago… - Movement …, 2016 - Wiley Online Library
Cognitive decline is one of the most frequent and disabling nonmotor features of Parkinson's
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …
disease. Around 30% of patients with Parkinson's disease experience mild cognitive …
Brain structural and functional connectivity in P arkinson's disease with freezing of gait
Objective To use a multimodal approach to assess brain structural pathways and resting
state (RS) functional connectivity abnormalities in patients with Parkinson's disease and …
state (RS) functional connectivity abnormalities in patients with Parkinson's disease and …
Gray and white matter imaging: A biomarker for cognitive impairment in early P arkinson's disease?
Background The aim of this work was to investigate the cortical and white matter changes
that underlie cognitive impairment in patients with incident Parkinson's disease (PD) disease …
that underlie cognitive impairment in patients with incident Parkinson's disease (PD) disease …
Deep brain stimulation and L-DOPA therapy: concepts of action and clinical applications in Parkinson's disease
L-DOPA is still the most effective pharmacological therapy for the treatment of motor
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …
symptoms in Parkinson's disease (PD) almost four decades after it was first used. Deep …
Safety and preliminary efficacy of intranasal insulin for cognitive impairment in Parkinson disease and multiple system atrophy: A double-blinded placebo-controlled …
Parkinson disease (PD) is associated with cognitive impairment. We aimed to determine the
effects of intranasal insulin (INI) on cognition and motor performance in PD. This was a proof …
effects of intranasal insulin (INI) on cognition and motor performance in PD. This was a proof …
Cognitive impairment in Parkinson's disease: An updated overview focusing on emerging pharmaceutical treatment approaches
Cognitive impairment in patients with Parkinson's disease (PD) is one of the commonest and
most disabling non-motor manifestations during the course of the disease. The clinical …
most disabling non-motor manifestations during the course of the disease. The clinical …