Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications

R Datta, TM Heaster, JT Sharick… - … of biomedical optics, 2020 - spiedigitallibrary.org
Significance: Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique to
distinguish the unique molecular environment of fluorophores. FLIM measures the time a …

Fluorescence lifetime imaging microscopy

B Torrado, B Pannunzio, L Malacrida… - Nature Reviews …, 2024 - nature.com
Fluorescence lifetime imaging microscopy (FLIM) is a powerful technique offering profound
insights into a broad spectrum of biological processes such as metabolic imaging, protein …

Artificial spherical chromatophore nanomicelles for selective CO2 reduction in water

J Yu, L Huang, Q Tang, SB Yu, QY Qi, J Zhang, D Ma… - Nature …, 2023 - nature.com
In nature, photosynthetic organelles harness solar radiation to produce energy-rich
compounds from water and atmospheric CO2 via exquisite supramolecular assemblies …

Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies

MC Hardenberg, T Sinnige, S Casford… - Journal of molecular …, 2021 - academic.oup.com
Misfolded α-synuclein is a major component of Lewy bodies, which are a hallmark of
Parkinson's disease (PD). A large body of evidence shows that α-synuclein can aggregate …

Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy

PA Summers, BW Lewis, J Gonzalez-Garcia… - Nature …, 2021 - nature.com
Guanine rich regions of oligonucleotides fold into quadruple-stranded structures called G-
quadruplexes (G4s). Increasing evidence suggests that these G4 structures form in vivo and …

Tailored self-assembled photocatalytic nanofibres for visible-light-driven hydrogen production

J Tian, Y Zhang, L Du, Y He, XH **, S Pearce… - Nature Chemistry, 2020 - nature.com
The creation of efficient artificial systems that mimic natural photosynthesis represents a key
current challenge. Here, we describe a high-performance recyclable photocatalytic core …

A transient pool of nuclear F-actin at mitotic exit controls chromatin organization

C Baarlink, M Plessner, A Sherrard, K Morita… - Nature cell …, 2017 - nature.com
Re-establishment of nuclear structure and chromatin organization after cell division is
integral for genome regulation or development and is frequently altered during cancer …

Microscale geometrical modulation of PIEZO1 mediated mechanosensing through cytoskeletal redistribution

HJ Wang, Y Wang, SS Mirjavadi, T Andersen… - Nature …, 2024 - nature.com
The microgeometry of the cellular microenvironment profoundly impacts cellular behaviors,
yet the link between it and the ubiquitously expressed mechanosensitive ion channel …

CASPI: collaborative photon processing for active single-photon imaging

J Lee, A Ingle, JV Chacko, KW Eliceiri… - Nature …, 2023 - nature.com
Image sensors capable of capturing individual photons have made tremendous progress in
recent years. However, this technology faces a major limitation. Because they capture scene …

Luminescent sensing and imaging of oxygen: Fierce competition to the Clark electrode

OS Wolfbeis - BioEssays, 2015 - Wiley Online Library
Luminescence‐based sensing schemes for oxygen have experienced a fast growth and are
in the process of replacing the Clark electrode in many fields. Unlike electrodes, sensing is …