Invasive fungal diseases in Africa: a critical literature review
Invasive fungal diseases (IFDs) are of huge concern in resource-limited settings, particularly
in Africa, due to the unavailability of diagnostic armamentarium for IFDs, thus making …
in Africa, due to the unavailability of diagnostic armamentarium for IFDs, thus making …
Nanotechnology-based approaches for voriconazole delivery applied to invasive fungal infections
L de Almeida Campos, MT Fin, KS Santos… - Pharmaceutics, 2023 - mdpi.com
Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …
Divergent neuroimmune signatures in the cerebrospinal fluid predict differential gender-specific survival among patients with HIV-associated cryptococcal meningitis
Introduction Survival among people with HIV-associated cryptococcal meningitis (CM)
remains low, particularly among women, despite the currently optimal use of antifungal …
remains low, particularly among women, despite the currently optimal use of antifungal …
Determining the burden of fungal infections in Zimbabwe
Zimbabwe currently faces several healthcare challenges, most notably HIV and associated
infections including tuberculosis (TB), malaria and recently outbreaks of cholera, typhoid …
infections including tuberculosis (TB), malaria and recently outbreaks of cholera, typhoid …
Prevalence of cryptococcal meningitis among people living with human immuno-deficiency virus and predictors of mortality in adults on induction therapy in Africa: A …
SGY Muzazu, DG Assefa, C Phiri, T Getinet… - Frontiers in …, 2022 - frontiersin.org
Background Cryptococcal meningitis (CM) is a leading cause of adult meningitis in countries
with a high burden of HIV. It has remained a significant cause of morbidity and mortality in …
with a high burden of HIV. It has remained a significant cause of morbidity and mortality in …
Impact of COVID-19 on the utilization of HIV testing and Linkage Services in Sierra Leone: experience from Three Public Health Facilities in Freetown
The COVID-19 pandemic adversely affected the delivery of essential health services
globally. In this study, we aimed to assess the impact of the pandemic on HIV testing and …
globally. In this study, we aimed to assess the impact of the pandemic on HIV testing and …
An Alternative Diagnostic Method for C. neoformans: Preliminary Results of Deep-Learning Based Detection Model
Cryptococcus neoformans is an opportunistic fungal pathogen with significant medical
importance, especially in immunosuppressed patients. It is the causative agent of …
importance, especially in immunosuppressed patients. It is the causative agent of …
HIV viral suppression at different thresholds and duration of treatment in the dolutegravir treatment era in Sierra Leone: a nationwide survey
JW Song, G Yang, MN Kamara, W Sun, Q Guan… - Virology Journal, 2023 - Springer
Introduction Viral load assessment for people living with HIV is key for monitoring treatment
and achieving the 95-95-95. In this study, we aimed to assess the degree of viral …
and achieving the 95-95-95. In this study, we aimed to assess the degree of viral …
Epidemiology of Cryptococcus and cryptococcosis in Western Africa
CL Akaihe, EI Nweze - Mycoses, 2021 - Wiley Online Library
Cryptococcosis is a serious and sometimes fatal fungal disease caused by Cryptococcus
species. Worldwide, it is estimated to kill over 180 000 annually, with 75% of deaths …
species. Worldwide, it is estimated to kill over 180 000 annually, with 75% of deaths …
All-cause mortality of hospitalised patients with suspected COVID-19 in Sierra Leone: a prospective cohort study
O Farrant, M Baldeh, JB Kamara, E Bailey, S Sevalie… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To study the mortality of patients with COVID-19 in Sierra Leone, to explore the
factors associated with mortality during the COVID-19 pandemic and to highlight the …
factors associated with mortality during the COVID-19 pandemic and to highlight the …