Interpretation of OCT and OCTA images from a histological approach: Clinical and experimental implications

N Cuenca, I Ortuño-Lizarán, X Sanchez-Saez… - Progress in retinal and …, 2020 - Elsevier
Optical coherence tomography (OCT) and OCT angiography (OCTA) have been a
technological breakthrough in the diagnosis, treatment, and follow-up of many retinal …

Stimulation strategies for improving the resolution of retinal prostheses

W Tong, H Meffin, DJ Garrett, MR Ibbotson - Frontiers in neuroscience, 2020 - frontiersin.org
Electrical stimulation using implantable devices with arrays of stimulating electrodes is an
emerging therapy for neurological diseases. The performance of these devices depends …

Protective effects of the bilobalide on retinal oxidative stress and inflammation in streptozotocin-induced diabetic rats

Q Su, J Dong, D Zhang, L Yang, R Roy - Applied Biochemistry and …, 2022 - Springer
Diabetic retinopathy (DR) is a diabetes mellitus (DM) complication that causes visual acuity
impairment and loss of sight in the working population, mainly in developed countries …

Retinal explant culture: a platform to investigate human neuro‐retina

A Murali, CA Ramlogan‐Steel… - Clinical & …, 2019 - Wiley Online Library
The retina is the tissue responsible for light detection, in which retinal neurons convert light
energy into electrical signals to be transported towards the visual cortex. Damage of retinal …

[HTML][HTML] Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration

A Salas, A Duarri, L Fontrodona, DM Ramírez… - … Therapy Methods & …, 2021 - cell.com
Photoreceptor loss is the principal cause of blindness in retinal degenerative diseases
(RDDs). Whereas some therapies exist for early stages of RDDs, no effective treatment is …

Improved visual acuity using a retinal implant and an optimized stimulation strategy

W Tong, M Stamp, NV Apollo, K Ganesan… - Journal of neural …, 2019 - iopscience.iop.org
Objective. Retinal prosthetic devices hold great promise for the treatment of retinal
degenerative diseases such as retinitis pigmentosa and age-related macular degeneration …

Compensation of inner retina to early-stage photoreceptor degeneration in a RhoP23H/+ mouse model of retinitis pigmentosa

B Wang, RK Arbuckle, KA Davoli, OD Clinger… - Experimental Eye …, 2024 - Elsevier
Retinitis pigmentosa (RP) is an inherited retinal disorder characterized by the degeneration
of photoreceptors. Rho P23H/+ mice, which carry a Pro23His mutation in the RHODOPSIN …

[HTML][HTML] Topical brimonidine or intravitreal BDNF, CNTF, or bFGF protect cones against phototoxicity

FJ Valiente-Soriano, A Ortín-Martínez… - … Vision Science & …, 2019 - iovs.arvojournals.org
Purpose: To develop a focal photoreceptor degeneration model by blue light-emitting diode
(LED)-induced phototoxicity (LIP) and investigate the protective effects of topical brimonidine …

3D electronic implants in subretinal space: long-term follow-up in rodents

MB Bhuckory, BY Wang, ZC Chen, A Shin… - Biomaterials, 2024 - Elsevier
Clinical results with photovoltaic subretinal prosthesis (PRIMA) demonstrated restoration of
sight via electrical stimulation of the interneurons in degenerated retina, with resolution …

Extracellular vesicles as a potential therapeutic for age-related macular degeneration

LLC Chow, B Mead - Neural Regeneration Research, 2023 - journals.lww.com
Age-related macular degeneration is a major global cause of central visual impairment and
severe vision loss. With an aging population, the already immense economic burden of …