Myotonic dystrophy is the most common type of muscular dystrophy in adults and is
characterised by progressive myopathy, myotonia, and multiorgan involvement. Two …

Myotonic dystrophy (DM) is the most common adult muscular dystrophy, characterized by
autosomal dominant progressive myopathy, myotonia and multiorgan involvement. To date …

The RNA-mediated disease model for myotonic dystrophy (DM) proposes that microsatellite
C (C) TG expansions express toxic RNAs that disrupt splicing regulation by altering MBNL1 …

Myotonic dystrophy types 1 and 2 are progressive multisystemic disorders with potential
brain involvement. We compared 22 myotonic dystrophy type 1 and 22 myotonic dystrophy …

Molecular therapeutics for myotonic dystrophy will probably bridge the translational gap
between bench and bedside in the near future. There will still be a requirement for clinical …

Objective: To systematically review brain imaging studies in myotonic dystrophy type 1
(DM1). Methods: We searched Embase (index period 1974–2016) and MEDLINE (index …

Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem
disorders of genetic origin. Progressive muscular weakness, atrophy and myotonia are the …

The myotonic dystrophies are the commonest cause of adult-onset muscular dystrophy.
Phenotypes of DM1 and DM2 are similar, but there are some important differences …

Myotonic dystrophy (DM) of type 1 and 2 (DM1 and DM2) are inherited autosomal dominant
diseases caused by dynamic and unstable expanded microsatellite sequences (CTG and …

Objectives Central nervous system involvement is one important clinical aspect of myotonic
dystrophy type 1 and 2 (DM1 and DM2). We assessed CNS involvement DM1 and DM2 by …