Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.
CE Boström, P Gerde, A Hanberg… - Environmental …, 2002 - ehp.niehs.nih.gov
Polycyclic aromatic hydrocarbons (PAHs) are formed during incomplete combustion.
Domestic wood burning and road traffic are the major sources of PAHs in Sweden. In …
Domestic wood burning and road traffic are the major sources of PAHs in Sweden. In …
Mitochondrial DNA damage and its consequences for mitochondrial gene expression
SD Cline - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2012 - Elsevier
How mitochondria process DNA damage and whether a change in the steady-state level of
mitochondrial DNA damage (mtDNA) contributes to mitochondrial dysfunction are questions …
mitochondrial DNA damage (mtDNA) contributes to mitochondrial dysfunction are questions …
Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons.
K Sundberg, AS Johansson, G Stenberg… - …, 1998 - academic.oup.com
Previous studies have identified allelic variants of the human glutathione transferase (GST)
Pi gene and showed that the two different encoded proteins with isoleucine (GSTP1-1/I-105) …
Pi gene and showed that the two different encoded proteins with isoleucine (GSTP1-1/I-105) …
Exposure to polycyclic aromatic hydrocarbons: bulky DNA adducts and cellular responses
F Henkler, K Stolpmann, A Luch - Molecular, Clinical and Environmental …, 2012 - Springer
Environmental and dietary carcinogens such as polycyclic aromatic hydrocarbons (PAHs)
have been intensively studied for decades. Although the genotoxicity of these compounds is …
have been intensively studied for decades. Although the genotoxicity of these compounds is …
Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase
H Ling, JM Sayer, BS Plosky, H Yagi… - Proceedings of the …, 2004 - National Acad Sciences
The first occupation-associated cancers to be recognized were the sooty warts (cancers of
the scrotum) suffered by chimney sweeps in 18th century England. In the 19th century, high …
the scrotum) suffered by chimney sweeps in 18th century England. In the 19th century, high …
Assessing the impact of Benzo[a]pyrene on Marine Mussels: Application of a novel targeted low density microarray complementing classical biomarker responses
Despite the increasing use of mussels in environmental monitoring and ecotoxicological
studies, their genomes and gene functions have not been thoroughly explored. Several …
studies, their genomes and gene functions have not been thoroughly explored. Several …
DNA adducts: biological markers of exposure and potential applications to risk assessment
DK La, JA Swenberg - Mutation Research/Reviews in Genetic Toxicology, 1996 - Elsevier
DNA adducts have been investigated extensively during the past decade. This research has
been advanced, in part, by the development of ultrasensitive analytical methods, such as …
been advanced, in part, by the development of ultrasensitive analytical methods, such as …
[PDF][PDF] Potential of watermelon (citrullis lanatus) peel extract in attenuating benzo [a] pyrene exposure-induced molecular damage in liver cells in vitro
Abstract Benzo [a] pyrene (B [a] P), a ubiquitous and prototypical environmental and dietary
toxicant, promotes oxidative stress and DNA damage. Plant parts such as watermelon …
toxicant, promotes oxidative stress and DNA damage. Plant parts such as watermelon …
Structure and mechanism of error-free replication past the major benzo [a] pyrene adduct by human DNA polymerase κ
Abstract Benzo [a] pyrene (BP) is a well-known and frequently encountered carcinogen
which generates a bulky DNA adduct (+)-trans-10 S-BP-N2-dG (BP-dG) in cells. DNA …
which generates a bulky DNA adduct (+)-trans-10 S-BP-N2-dG (BP-dG) in cells. DNA …
Dibenzo [a, l] pyrene-induced DNA adduction, tumorigenicity, and Ki-ras oncogene mutations in strain A/J mouse lung.
AK Prahalad, JA Ross, GB Nelson, BC Roop… - …, 1997 - academic.oup.com
Abstract Dibenzo [a, l] pyrene (DB [a, l] P), an environmental polycyclic aromatic
hydrocarbon, is the most potent carcinogen ever tested in mouse skin and rat mammary …
hydrocarbon, is the most potent carcinogen ever tested in mouse skin and rat mammary …