The dopaminergic basis of human behaviors: A review of molecular imaging studies
A Egerton, MA Mehta, AJ Montgomery… - Neuroscience & …, 2009 - Elsevier
This systematic review describes human molecular imaging studies which have investigated
alterations in extracellular DA levels during performance of behavioral tasks. Whilst …
alterations in extracellular DA levels during performance of behavioral tasks. Whilst …
Evidence for striatal dopamine release during a video game
Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour,
attention, and sensorimotor integration,. Binding of the radioligand 11C-labelled raclopride …
attention, and sensorimotor integration,. Binding of the radioligand 11C-labelled raclopride …
Cognitive deficits and striato-frontal dopamine release in Parkinson's disease
Idiopathic Parkinson's disease (PD) is often accompanied by a pattern of executive deficits
similar to those found in patients with frontal lobe lesions. We investigated whether such …
similar to those found in patients with frontal lobe lesions. We investigated whether such …
Tracer kinetic modeling in PET
RE Carson - Positron emission tomography: Basic sciences, 2005 - Springer
The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with
modern instrumentation are key components to successful developments in PET. Clever …
modern instrumentation are key components to successful developments in PET. Clever …
In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates
A Heinz, JD Higley, JG Gorey… - American Journal of …, 1998 - Am Psychiatric Assoc
OBJECTIVE: Studies on brain serotonin metabolism in human and nonhuman primates
have indicated that dysfunction of serotonin transmission may play a role in the biological …
have indicated that dysfunction of serotonin transmission may play a role in the biological …
A novel method for noninvasive detection of neuromodulatory changes in specific neurotransmitter systems
NM Alpert, RD Badgaiyan, E Livni, AJ Fischman - Neuroimage, 2003 - Elsevier
Over the last decade, it has become possible to study theories of cognition using positron
emission tomography (PET) and functional magnetic resonance imaging (fMRI). These …
emission tomography (PET) and functional magnetic resonance imaging (fMRI). These …
In vivo imaging of neuromodulatory synaptic transmission using PET: a review of relevant neurophysiology
Recent data from positron emission tomography (PET) imaging studies suggest the
possibility of studying synaptic transmission in vivo in humans. The approach will require a …
possibility of studying synaptic transmission in vivo in humans. The approach will require a …
In vivo detection of striatal dopamine release during reward: a PET study with [11C] raclopride and a single dynamic scan approach
Anew simple method is proposed to detect, using PET and [11C] raclopride, changes in
striatal extracellular dopamine concentration during a rewarded effortful task. This approach …
striatal extracellular dopamine concentration during a rewarded effortful task. This approach …
Pain activation of human supraspinal opioid pathways as demonstrated by [11C]-carfentanil and positron emission tomography (PET)
The role of the supraspinal endogenous opioid system in pain processing has been
investigated in this study using positron emission tomography imaging of [11C]-carfentanil, a …
investigated in this study using positron emission tomography imaging of [11C]-carfentanil, a …
A linear model for estimation of neurotransmitter response profiles from dynamic PET data
The parametric ntPET model (p-ntPET) estimates the kinetics of neurotransmitter release
from dynamic PET data with receptor–ligand radiotracers. Here we introduce a linearization …
from dynamic PET data with receptor–ligand radiotracers. Here we introduce a linearization …