Exploring the HSA/DNA/lung cancer cells binding behavior of p-Synephrine, a naturally occurring phenyl ethanol amine with anti-adipogenic activity: multi …

R Taheri, N Hamzkanlu, Y Rezvani… - Journal of Molecular …, 2022 - Elsevier
As a phenolic amine, p-Synephrine (SN) is known to exhibit lipolytic properties as well as
enhancing energy expenditure, which can be an excellent alternative to ephedra as a …

New perspective of the ternary complex of nano-curcumin with β-lactoglobulin in the presence of α-lactalbumin: Spectroscopic and molecular dynamic investigations

M Tabasi, P Maghami, Z Amiri-Tehranizadeh… - Journal of Molecular …, 2023 - Elsevier
Understanding the interaction between nano-curcumin (Nano Cur) and proteins is essential
for elucidating the potential therapeutic applications of curcumin in nano formulations. In this …

Revealing the potential of theaflavin to reduce egg allergenicity at the molecular level: A study of the binding affinity of theaflavin to egg white lysozyme

Y Li, M Li, Q Li, F Geng, Q Wang, N Gan, S Li… - Food and Bioprocess …, 2024 - Springer
Tea polyphenols are considered one of the effective means to reduce protein sensitization,
and it is necessary to study their binding mechanism. Therefore, this study investigated the …

In vitro interactions of esculin and esculetin with bovine hemoglobin alter its structure and inhibit aggregation: insights from spectroscopic and computational studies

S Lyndem, U Hazarika, A Bhatta, V Prakash… - New Journal of …, 2023 - pubs.rsc.org
Hemoglobin serves a multitude of biological functions and its activity and stability are
influenced by structural alterations. Fibrillation of this protein is one such complication that …

Interactions of Turmeric-and Curcumin-Functionalized Gold Nanoparticles with Human Serum Albumin: Exploration of Protein Corona Formation, Binding …

K Baruah, AK Singh, K Kumari, DL Nongbri, AN Jha… - Langmuir, 2023 - ACS Publications
In order to better understand the bioavailability and biocompatibility of polyphenol-assisted
surface-modified bioengineered nanoparticles in nanomedicine applications, here, we …

Ca2+-promoted free radical grafting of whey protein to EGCG: As a novel nanocarrier for the encapsulation of apigenin

Y Wang, H Guo, T Zhao, J Chen, D Cheng - Food Chemistry, 2024 - Elsevier
Whey protein (WP) is often used as a delivery carrier due to its superior biological activity
and nutritional value. Covalent binding of WP to epigallocatechin gallate (EGCG) can …

Ascorbic and salicylic acids modulate the binding interactions of an emergency contraceptive pill levonorgestrel to a model transport protein: Insights from …

OJ Avwioroko, AA Anigboro, ME Adeleye… - Journal of Molecular …, 2024 - Elsevier
Serum proteins generally help to transport and distribute drug molecules within the body. In
this study, the binding characteristics of bovine serum albumin (BSA) with levonorgestrel …

A novel angiotensin-I-converting enzyme inhibitory peptide from oyster: Simulated gastro-intestinal digestion, molecular docking, inhibition kinetics and …

H Chen, Y Chen, H Zheng, X **ang, L Xu - Frontiers in Nutrition, 2022 - frontiersin.org
In this study, a novel peptide, AEYLCEAC with high angiotensin-I-converting enzyme
inhibitory (ACEI) activity was screened from oyster (Crassostrea gigas) hydrolysates, which …

Non-covalent binding interaction of bioactive coumarin esculetin with calf thymus DNA and yeast transfer RNA: A detailed investigation to decipher the binding …

S Quraishi, D Saha, K Kumari, AN Jha… - International Journal of …, 2024 - Elsevier
Esculetin is a well-known coumarin derivative found abundantly in nature possessing an
extensive array of pharmacological and therapeutic properties. Consequently, to …

Effects of ultraviolet radiation and reactive oxygen species on the structure and ligand-binding ability of human serum albumin for norfloxacin

J Zhang, Q Ma, Y Li, Y Liao, H Wang - Journal of Molecular Liquids, 2024 - Elsevier
To explore the influence of ultraviolet radiation (UV) and reactive oxygen species (ROS) on
the structure and ligand-binding ability of human serum albumin (HSA) for norfloxacin …