[HTML][HTML] Vitamin D determinants, status, and antioxidant/anti-inflammatory-related effects in cardiovascular risk and disease: not the last word in the controversy

G Della Nera, L Sabatino, M Gaggini, F Gorini… - Antioxidants, 2023 - mdpi.com
Beyond its key role in calcium homeostasis, vitamin D has been found to significantly affect
the cardiovascular (CV) system. In fact, low vitamin D levels have been associated with …

Targeting the platelet-activating factor receptor (PAF-R): antithrombotic and anti-atherosclerotic nutrients

R Harishkumar, S Hans, JE Stanton, AM Grabrucker… - Nutrients, 2022 - mdpi.com
Platelet-activating factor (PAF) is a lipid mediator that interacts with its receptor (PAF-R) to
carry out cell signalling. However, under certain conditions the binding of PAF to PAF-R …

Vitamin D in atherosclerosis and cardiovascular events

F Carbone, L Liberale, P Libby… - European heart …, 2023 - academic.oup.com
Both experimental and clinical findings linking vitamin D to cardiovascular (CV) risk have
prompted consideration of its supplementation to improve overall health. Yet several meta …

[HTML][HTML] Multifaceted Roles of Vitamin D for Diabetes: From Immunomodulatory Functions to Metabolic Regulations

CY Park, S Shin, SN Han - Nutrients, 2024 - mdpi.com
Numerous studies have established associations between vitamin D and diabetes. The
vitamin D receptor is widely distributed throughout the human body, including in pancreatic …

[HTML][HTML] Role of lowered level of serum vitamin D on diabetic foot ulcer and its possible pathomechanism: A systematic review, meta-analysis, and meta-regression

M Iqhrammullah, TF Duta, M Alina, I Qanita… - Diabetes Epidemiology …, 2024 - Elsevier
Aim To investigate the association between serum vitamin D (SVD) level and DFU
development and to emphasize the involved pathomechanism. Methods The search was …

[HTML][HTML] Ticlopidine induces embryonic development toxicity and hepatotoxicity in zebrafish by upregulating the oxidative stress signaling pathway

R Xu, P Xu, H Wei, Y Huang, X Zhu, C Lin, Z Yan… - Ecotoxicology and …, 2023 - Elsevier
Ticlopidine exerts its anti-platelet effects mainly by antagonizing platelet p2y12 receptors.
Previously, a few studies have shown that ticlopidine can induce liver injury, but the exact …

Vitamin D status affects proteomic profile of HDL-associated proteins and inflammatory mediators in dyslipidemia

H Mousa, RM Razali, SM Zughaier - The Journal of Nutritional …, 2024 - Elsevier
Vitamin D deficiency and dyslipidemia have substantial implications for human health
globally. Vitamin D is essential for bone metabolism and immune modulation, and its …

Vitamin D as a modulator of molecular pathways involved in CVDs: evidence from preclinical studies

S Dutta, S Aboo, A Ismail - Life Sciences, 2024 - Elsevier
Vitamin D deficiency (VDD) is a widespread global health issue, affecting nearly a billion
individuals worldwide, and mounting evidence links it to an increased risk of cardiovascular …

Vitamin D and ischemic stroke-association, mechanisms, and therapeutics

P Cui, H Hou, B Song, Z **a, Y Xu - Ageing Research Reviews, 2024 - Elsevier
Confronting the rising tide of ischemic stroke and its associated mortality and morbidity with
ageing, prevention and acute management of ischemic stroke is of paramount importance …

Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes

S Hamamah, OC Iatcu, M Covasa - Nutrients, 2024 - mdpi.com
Nutrition is one of the most influential environmental factors in both taxonomical shifts in gut
microbiota as well as in the development of type 2 diabetes mellitus (T2DM). Emerging …