Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Functionalized nanomaterials capable of crossing the blood–brain barrier

S Zha, H Liu, H Li, H Li, KL Wong, AH All - ACS nano, 2024 - ACS Publications
The blood–brain barrier (BBB) is a specialized semipermeable structure that highly
regulates exchanges between the central nervous system parenchyma and blood vessels …

Research status of dendrimer micelles in tumor therapy for drug delivery

X Wang, M Zhang, Y Li, H Cong, B Yu, Y Shen - Small, 2023 - Wiley Online Library
Dendrimers are a family of polymers with highly branched structure, well‐defined
composition, and extensive functional groups, which have attracted great attention in …

mRNA nanodelivery systems: targeting strategies and administration routes

M Yuan, Z Han, Y Liang, Y Sun, B He… - Biomaterials …, 2023 - spj.science.org
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …

Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment

L Liu, Y Zhang, X Li, J Deng - Journal of Nanobiotechnology, 2023 - Springer
Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its
diagnosis and treatment are still impeded by our limited understanding of its etiology …

[HTML][HTML] Solubilization techniques used for poorly water-soluble drugs

B **e, Y Liu, X Li, P Yang, W He - Acta Pharmaceutica Sinica B, 2024 - Elsevier
Currently, about 40% of approved drugs and nearly 90% of drug candidates are poorly
water-soluble drugs. Low solubility reduces the likelihood that these drugs can be effectively …

Dendrimers as nanocarriers for the delivery of drugs obtained from natural products

H An, X Deng, F Wang, P Xu, N Wang - Polymers, 2023 - mdpi.com
Natural products have proven their value as drugs that can be therapeutically beneficial in
the treatment of various diseases. However, most natural products have low solubility and …

[HTML][HTML] Sensitive and responsive upconversion nanoprobes for fluorescence turn-on detection of glucose concentration

S Zha, H Li, GL Law, KL Wong, AH All - Materials & Design, 2023 - Elsevier
Various approaches for detecting glucose concentration in real time are emerging at a
breakneck pace. Glucose metabolism is closely linked to severe pathological events, which …

Dendrimers as drug delivery systems for oncotherapy: Current status of promising applications

S Sueyoshi, JV Silva, F Guizze, J Giarolla - International Journal of …, 2024 - Elsevier
Cancer affects millions of people worldwide, causing death and serious health problems.
Despite significant investment in the development of new anticancer compounds, there are …

Branched Polymers: Synthesis and Application

G Shao, A Li, Y Liu, B Yuan, W Zhang - Macromolecules, 2023 - ACS Publications
Branched polymers have aroused great interest due to their less chain entanglement, high
concentration of chain terminals, good solubility, and low viscosity in melts and solutions. In …