There is no consensus on the optimal pCO2 levels in the newborn. We reviewed the effects
of hypercapnia and hypocapnia and existing carbon dioxide thresholds in neonates. A …

Despite improvements in the mortality rates of preterm infants, rates of germinal matrix
intraventricular hemorrhage (IVH) have remained static with an overall incidence of 25% in …

Cerebrovascular lesions, mainly germinal matrix hemorrhage and ischemic injury to the
periventricular white matter, are major causes of adverse neurodevelopmental outcome in …

Background Tolerating higher partial pressure of carbon dioxide (pCO 2) in mechanically
ventilated, extremely low birthweight infants might reduce ventilator-induced lung injury and …

This review article focuses on neonatal respiratory physiology, mechanical ventilation of the
neonate and changes induced by anesthesia and surgery. Optimal ventilation techniques for …

The current bronchopulmonary dysplasia (BPD) is seen in infants born extremely premature,
with less severe respiratory distress syndrome (RDS) and who received prenatal steroids …

OBJECTIVE. The purpose of this work was to evaluate the impact of the implementation of a
ventilation protocol driven by registered respiratory therapists on respiratory outcomes of …

Context In adults, permissive hypercapnia reduces mortality and ventilation duration.
However, in preterm infants, the findings from past research regarding the efficacy and …

BACKGROUND: Congenital diaphragmatic hernia (CDH) is a potentially lethal anomaly
associated with pulmonary hypoplasia and persistent pulmonary hypertension. Permissive …

Aim Safe limits of arterial partial pressure of carbon dioxide (PaCO2) and acidosis in
premature infants are not well defined. Both respiratory and systemic illness along with …