Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …
saved several lives, reduced treatment costs and raised the quality of animal and human …
Multiepitope-based subunit vaccine design and evaluation against respiratory syncytial virus using reverse vaccinology approach
Respiratory syncytial virus (RSV) is primarily associated with respiratory disorders globally.
Despite the availability of information, there is still no competitive vaccine available for RSV …
Despite the availability of information, there is still no competitive vaccine available for RSV …
Targeting tumor lineage plasticity in hepatocellular carcinoma using an anti-CLDN6 antibody-drug conjugate
FE Kong, GM Li, YQ Tang, SY **, JHC Loong… - Science Translational …, 2021 - science.org
Tumor lineage plasticity is emerging as a critical mechanism of therapeutic resistance and
tumor relapse. Highly plastic tumor cells can undergo phenotypic switching to a drug …
tumor relapse. Highly plastic tumor cells can undergo phenotypic switching to a drug …
Differential regulation of Na+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition
MTX Nguyen, DH Lee, E Delpire… - American Journal of …, 2013 - journals.physiology.org
During angiotensin II (ANG II)-dependent hypertension, ANG II stimulates, while
hypertension inhibits, Na+ transporter activity to balance Na+ output to input. This study tests …
hypertension inhibits, Na+ transporter activity to balance Na+ output to input. This study tests …
Protection by hydroxychloroquine prevents placental injury in obstetric antiphospholipid syndrome
J Liu, L Zhang, Y Tian, S Wan, M Hu… - Journal of Cellular …, 2022 - Wiley Online Library
Obstetric antiphospholipid syndrome (OAPS) is mediated by antiphospholipid antibodies
(aPLs, and anti‐β2 glycoprotein I antibody is the main pathogenic antibody), and recurrent …
(aPLs, and anti‐β2 glycoprotein I antibody is the main pathogenic antibody), and recurrent …
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy
Bacteria of the genus Brucella cause brucellosis, one of the world's most common zoonotic
diseases. A major contributor to Brucella's virulence is the ability to circumvent host immune …
diseases. A major contributor to Brucella's virulence is the ability to circumvent host immune …
Peptide antibodies in clinical laboratory diagnostics
NH Trier, G Houen - Advances in clinical chemistry, 2017 - Elsevier
Peptide antibodies, with their high specificities and affinities, are invaluable reagents for
peptide and protein recognition in biological specimens. Depending on the application and …
peptide and protein recognition in biological specimens. Depending on the application and …
[HTML][HTML] Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer
Diagnosis and assessment of patients with prostate cancer is dependent on accurate
interpretation and grading of histopathology. However, morphology does not necessarily …
interpretation and grading of histopathology. However, morphology does not necessarily …
Human intelectin-1 (ITLN1) genetic variation and intestinal expression
EB Nonnecke, PA Castillo, AE Dugan, F Almalki… - Scientific reports, 2021 - nature.com
Intelectins are ancient carbohydrate binding proteins, spanning chordate evolution and
implicated in multiple human diseases. Previous GWAS have linked SNPs in ITLN1 (also …
implicated in multiple human diseases. Previous GWAS have linked SNPs in ITLN1 (also …
Specialized stellate cells offer a privileged route for rapid water flux in Drosophila renal tubule
Insects are highly successful, in part through an excellent ability to osmoregulate. The renal
(Malpighian) tubules can secrete fluid faster on a per-cell basis than any other epithelium …
(Malpighian) tubules can secrete fluid faster on a per-cell basis than any other epithelium …