Conspectus The term RNA editing refers to any structural change in an RNA molecule (eg.,
insertion, deletion, or base modification) that changes its coding properties and is not a …

Recruiting the endogenous editing enzyme adenosine deaminase acting on RNA (ADAR)
with tailored guide RNAs for adenosine-to-inosine (A-to-I) RNA base editing is promising for …

Adenosine deaminases acting on RNA (ADARs) are enzymes that catalyze the hydrolytic
deamination of adenosine to inosine. The editing feature of ADARs has garnered much …

A-to-I mRNA editing in animals is mediated by ADARs, but the mechanism underlying
sexual stage-specific A-to-I mRNA editing in fungi remains unknown. Here, we show that the …

RNA editing is a highly conserved process. Adenosine deaminase acting on RNA (ADAR)
mediated deamination of adenosine (A-to-I editing) is associated with human disease and …

Over recent years, zinc-dependent deaminases have attracted increasing interest as key
components of nucleic acid editing tools that can generate point mutations at specific sites in …

Abstract Adenosine-to-inosine (A-to-I) editing of RNA, catalyzed by adenosine deaminase
acting on RNA (ADAR) enzymes, is a prevalent RNA modification in mammals. It has been …

Inosine (I), resulting from the deamination of adenosine (A), is a prominent modification in
the human transcriptome. The enzymes responsible for the conversion of adenosine to …

Abstract Adenosine-to-inosine (A-to-I) RNA editing is a prevalent RNA modification essential
for cell survival. The process is catalyzed by the Adenosine Deaminase Acting on RNA …

Adenosine Deaminases Acting on RNA (ADARs) convert adenosine to inosine in duplex
RNA, and through the delivery of guide RNAs, can be directed to edit specific adenosine …