Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

The development and progression of diabetic kidney disease (DKD), a highly prevalent
complication of diabetes mellitus, are influenced by both genetic and environmental factors …

Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in patients with
diabetes mellitus and the leading cause of end-stage renal disease in the world. The most …

Diabetes is a chronic disease, characterized by hyperglycemia, which refers to the elevated
levels of glucose in the blood, due to the inability of the body to produce or use insulin …

The incidence of diabetes and its associated micro-and macrovascular complications is
greatly increasing worldwide. The most prevalent vascular complications of both type 1 and …

Background High-throughput profiling of DNA methylation status of CpG islands is crucial to
understand the epigenetic regulation of genes. The microarray-based Infinium methylation …

The ability to estimate the age of the donor from recovered biological material at a crime
scene can be of substantial value in forensic investigations. Aging can be complex and is …

Diabetic retinopathy remains the major cause of blindness among working age adults.
Although a number of metabolic abnormalities have been associated with its development …

The burgeoning interest in the field of epigenetics has precipitated the need to develop
approaches to strengthen causal inference when considering the role of epigenetic …