[HTML][HTML] Hematopoietic cell transplantation in the treatment of pediatric acute myelogenous leukemia and myelodysplastic syndromes: guidelines from the American …

K Tarlock, ML Sulis, JH Chewning, JA Pollard… - … and Cellular Therapy, 2022 - Elsevier
The role of allogeneic hematopoietic stem cell transplantation (HCT) in the treatment of
acute myelogenous leukemia (AML) in children is reviewed and critically evaluated in this …

Challenges and advances in chimeric antigen receptor therapy for acute myeloid leukemia

J Marvin-Peek, BN Savani, OO Olalekan, B Dholaria - Cancers, 2022 - mdpi.com
Simple Summary Chimeric antigen receptor (CAR) therapy has increased treatment options
for many patients who have failed standard chemotherapy. So far, CAR therapy has been …

Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN

H Döhner, AH Wei, FR Appelbaum… - Blood, The Journal …, 2022 - ashpublications.org
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for
diagnosis and management of acute myeloid leukemia (AML) in adults are widely …

WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy

Y Fløisand, M Remberger, I Bigalke, D Josefsen… - Leukemia, 2023 - nature.com
Intensive induction chemotherapy achieves complete remissions (CR) in> 60% of patients
with acute myeloid leukemia (AML) but overall survival (OS) is poor for relapsing patients not …

Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113 AML patients

M Boyiadzis, MJ Zhang, K Chen, H Abdel-Azim… - Leukemia, 2023 - nature.com
We investigated the impact of the number of induction/consolidation cycles on outcomes of
3113 adult AML patients who received allogeneic hematopoietic cell transplantation (allo …

Longitudinal outcome over two decades of unrelated allogeneic stem cell transplantation for relapsed/refractory acute myeloid leukemia: an ALWP/EBMT analysis

A Nagler, M Ngoya, JE Galimard, M Labopin… - Clinical Cancer …, 2022 - AACR
Purpose: We evaluated outcomes of unrelated transplantation for primary
refractory/relapsed (ref/rel) acute myeloid leukemia (AML), comparing two cohorts according …

[HTML][HTML] Recent advances in nanomaterials for modulation of stem cell differentiation and its therapeutic applications

CD Kim, KM Koo, HJ Kim, TH Kim - Biosensors, 2024 - mdpi.com
Challenges in directed differentiation and survival limit the clinical use of stem cells despite
their promising therapeutic potential in regenerative medicine. Nanotechnology has …

Comparing cord blood transplantation and matched related donor transplantation in non-remission acute myeloid leukemia

Y Shimomura, T Sobue, S Hirabayashi, T Kondo… - Leukemia, 2022 - nature.com
Cord blood transplantation (CBT) is an alternative donor transplantation method and has the
advantages of rapid availability and the possibility of inducing a more potent graft-versus …

TP53 mutations in AML patients are associated with dismal clinical outcome irrespective of frontline induction regimen and allogeneic hematopoietic cell …

D Zhao, M Zarif, Q Zhou, JM Capo-Chichi, A Schuh… - Cancers, 2023 - mdpi.com
Simple Summary TP53 mutations are adverse-risk genetic aberrations in acute myeloid
leukemia (AML). The optimal treatment approach in patients with TP53-mutated (TP53 MUT) …

How I treat with maintenance therapy after allogeneic HCT

Z DeFilipp, YB Chen - Blood, 2023 - ashpublications.org
Disease relapse is the leading cause of failure for patients receiving allogeneic
hematopoietic cell transplantation (allo-HCT). Maintenance therapy administered after allo …