From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment
Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …
[HTML][HTML] The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours
The fifth edition of the World Health Organization (WHO) classification of urogenital tumours
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
Glioblastoma and other primary brain malignancies in adults: a review
Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …
United States. The annual incidence of primary malignant brain tumors is approximately 7 …
Cancer epigenetics in clinical practice
Cancer development is driven by the accumulation of alterations affecting the structure and
function of the genome. Whereas genetic changes disrupt the DNA sequence, epigenetic …
function of the genome. Whereas genetic changes disrupt the DNA sequence, epigenetic …
Glioma targeted therapy: insight into future of molecular approaches
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …
gliomas occur among all ages, more often seen in adults, which males are more susceptible …
[HTML][HTML] Glioblastoma hijacks neuronal mechanisms for brain invasion
Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …
Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …
Although the previous edition of this classification was published just 5 years earlier, in …
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …
medical therapies for meningioma patients, and new treatments have been encumbered by …
Combining machine learning and computational chemistry for predictive insights into chemical systems
Machine learning models are poised to make a transformative impact on chemical sciences
by dramatically accelerating computational algorithms and amplifying insights available from …
by dramatically accelerating computational algorithms and amplifying insights available from …
A clinically applicable integrative molecular classification of meningiomas
Meningiomas are the most common primary intracranial tumour in adults. Patients with
symptoms are generally treated with surgery as there are no effective medical therapies. The …
symptoms are generally treated with surgery as there are no effective medical therapies. The …