From patterns to patients: Advances in clinical machine learning for cancer diagnosis, prognosis, and treatment

K Swanson, E Wu, A Zhang, AA Alizadeh, J Zou - Cell, 2023 - cell.com
Machine learning (ML) is increasingly used in clinical oncology to diagnose cancers, predict
patient outcomes, and inform treatment planning. Here, we review recent applications of ML …

[HTML][HTML] The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours

H Moch, MB Amin, DM Berney, EM Compérat, AJ Gill… - European urology, 2022 - Elsevier
The fifth edition of the World Health Organization (WHO) classification of urogenital tumours
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …

Glioblastoma and other primary brain malignancies in adults: a review

LR Schaff, IK Mellinghoff - Jama, 2023 - jamanetwork.com
Importance Malignant primary brain tumors cause more than 15 000 deaths per year in the
United States. The annual incidence of primary malignant brain tumors is approximately 7 …

[HTML][HTML] Glioblastoma hijacks neuronal mechanisms for brain invasion

V Venkataramani, Y Yang, MC Schubert, E Reyhan… - Cell, 2022 - cell.com
Glioblastomas are incurable tumors infiltrating the brain. A subpopulation of glioblastoma
cells forms a functional and therapy-resistant tumor cell network interconnected by tumor …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J **g - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Ultra-fast deep-learned CNS tumour classification during surgery

C Vermeulen, M Pagès-Gallego, L Kester… - Nature, 2023 - nature.com
Central nervous system tumours represent one of the most lethal cancer types, particularly
among children. Primary treatment includes neurosurgical resection of the tumour, in which …

Clinical implications of the 2021 edition of the WHO classification of central nervous system tumours

C Horbinski, T Berger, RJ Packer, PY Wen - Nature Reviews Neurology, 2022 - nature.com
A new edition of the WHO classification of tumours of the CNS was published in 2021.
Although the previous edition of this classification was published just 5 years earlier, in …

Toward explainable artificial intelligence for precision pathology

F Klauschen, J Dippel, P Keyl… - Annual Review of …, 2024 - annualreviews.org
The rapid development of precision medicine in recent years has started to challenge
diagnostic pathology with respect to its ability to analyze histological images and …

Multimodal data fusion for cancer biomarker discovery with deep learning

S Steyaert, M Pizurica, D Nagaraj… - Nature machine …, 2023 - nature.com
Technological advances have made it possible to study a patient from multiple angles with
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …