The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted for the period beginning March 2008 through …

The development of novel, non-invasive techniques and standardization of protocols to
assess microvascular dysfunction have elucidated the key role of microvascular changes in …

Aims There is growing need for the identification of novel non-invasive methodologies for
the identification of individuals at risk for adverse cardiovascular (CV) events. We examined …

2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults:
Executive Summary | Circulation Science Volunteer Warning signs SearchSearch …

Objectives We performed a systematic review and meta-analysis to understand the role of
flow-mediated dilatation (FMD) of the brachial artery (BA) and peripheral arterial tonometry …

Background—Digital pulse amplitude augmentation in response to hyperemia is a novel
measure of peripheral vasodilator function that depends partially on endothelium-derived …

Endothelial dysfunction is a potential target for (pharmaceutical) intervention of several
systemic pathological conditions. We investigated the feasibility of the EndoPAT to evaluate …

The importance of endothelial dysfunction in the development and clinical expression of
cardiovascular disease is well recognized. Impaired endothelial function has been …

Objectives: The aim of the current study was to test the hypothesis that vascular and
endothelial functional responses to acute mental stress are abnormal in patients with apical …

Traditional cardiovascular risk (CV) factors based on the Framingham study have been used
to estimate the risk of CV events and determine target cholesterol levels for primary …