INTRODUCTION Understanding longitudinal plasma biomarker trajectories relative to brain
amyloid changes can help devise Alzheimer's progression assessment strategies …

Background Chronic liver diseases of all etiologies exist along a spectrum with varying
degrees of hepatic fibrosis. Despite accumulating evidence implying associations between …

Personality traits have been associated with the risk of dementia and Alzheimer's disease
neuropathology, including amyloid and tau. This study examines whether personality traits …

Objective Few studies have comprehensively examined how health and disease risk
influence Alzheimer's disease (AD) biomarkers. The present study examined the association …

Background and Objectives Prospective measures of plasma and cerebral MRI biomarkers
of Alzheimer disease (AD) and vascular neuropathology provide an opportunity to …

Abstract INTRODUCTION We examined midlife (1990–1992, mean age 57) and late‐life
(2011–2013, mean age 75) nonalcoholic fatty liver disease (NAFLD) and aminotransferase …

Background Blood-based biomarkers for Alzheimer's disease (AD) are promising to be used
in clinical settings. The liver is an important degradation organ of the body. Whether liver …

Abstract Background & Aims Transcription co‐activator factor 20 (TCF20) is a regulator of
transcription factors involved in extracellular matrix remodelling. In addition, TCF20 genomic …

Objectives Loneliness is associated with an elevated risk of dementia. There is mixed
evidence from imaging studies on whether loneliness is associated with neuropathology in …

ABSTRACT The Gut Microbiome-Liver-Brain Axis is a relatively novel construct with
promising potential to enhance our understanding of Alcohol Use Disorder (AUD) …