Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Schizophrenia—an overview

RA McCutcheon, TR Marques, OD Howes - JAMA psychiatry, 2020 - jamanetwork.com
Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

C Mu, X Dang, XJ Luo - Nature human behaviour, 2024 - nature.com
Dysfunction of brain resting-state functional networks has been widely reported in
psychiatric disorders. However, the causal relationships between brain resting-state …

[HTML][HTML] Using deep learning to investigate the neuroimaging correlates of psychiatric and neurological disorders: Methods and applications

S Vieira, WHL Pinaya, A Mechelli - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Deep learning (DL) is a family of machine learning methods that has gained considerable
attention in the scientific community, breaking benchmark records in areas such as speech …

Revisiting the functional anatomy of the human brain: toward a meta-networking theory of cerebral functions

G Herbet, H Duffau - Physiological Reviews, 2020 - journals.physiology.org
For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …

Multivariate brain-behaviour associations in psychiatric disorders

S Vieira, TAW Bolton, M Schöttner, L Baecker… - Translational …, 2024 - nature.com
Map** brain-behaviour associations is paramount to understand and treat psychiatric
disorders. Standard approaches involve investigating the association between one brain …

Common dysfunction of large-scale neurocognitive networks across psychiatric disorders

Z Sha, TD Wager, A Mechelli, Y He - Biological psychiatry, 2019 - Elsevier
Background Cognitive dysfunction is one of the most prominent characteristics of psychiatric
disorders. Currently, the neural correlates of cognitive dysfunction across psychiatric …

Machine learning in resting-state fMRI analysis

M Khosla, K Jamison, GH Ngo, A Kuceyeski… - Magnetic resonance …, 2019 - Elsevier
Abstract Machine learning techniques have gained prominence for the analysis of resting-
state functional Magnetic Resonance Imaging (rs-fMRI) data. Here, we present an overview …

Multi-site diagnostic classification of schizophrenia using discriminant deep learning with functional connectivity MRI

LL Zeng, H Wang, P Hu, B Yang, W Pu, H Shen… - …, 2018 - thelancet.com
Background A lack of a sufficiently large sample at single sites causes poor generalizability
in automatic diagnosis classification of heterogeneous psychiatric disorders such as …