Population genomics of Klebsiella pneumoniae
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …
Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria
Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …
membrane and an inner membrane, are an important and attractive system for studying the …
A genomic surveillance framework and genoty** tool for Klebsiella pneumoniae and its related species complex
Klebsiella pneumoniae is a leading cause of antimicrobial-resistant (AMR) healthcare-
associated infections, neonatal sepsis and community-acquired liver abscess, and is …
associated infections, neonatal sepsis and community-acquired liver abscess, and is …
Safety of bacteriophage therapy in severe Staphylococcus aureus infection
In this single-arm non-comparative trial, 13 patients in an Australian hospital with severe
Staphylococcus aureus infections were intravenously administered a good manufacturing …
Staphylococcus aureus infections were intravenously administered a good manufacturing …
Mating pair stabilization mediates bacterial conjugation species specificity
Bacterial conjugation mediates contact-dependent transfer of DNA from donor to recipient
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
bacteria, thus facilitating the spread of virulence and resistance plasmids. Here we describe …
Biological foundations of successful bacteriophage therapy
Bacteriophages (phages) are selective viral predators of bacteria. Abundant and ubiquitous
in nature, phages can be used to treat bacterial infections (phage therapy), including …
in nature, phages can be used to treat bacterial infections (phage therapy), including …
Assessment of activity and resistance mechanisms to cefepime in combination with the novel β-lactamase inhibitors zidebactam, taniborbactam, and enmetazobactam …
The global distribution of carbapenemases such as KPC, OXA-48, and metallo-β-
lactamases (MBLs) gives cause for concern, as these enzymes are not inhibited by classical …
lactamases (MBLs) gives cause for concern, as these enzymes are not inhibited by classical …
[HTML][HTML] Molecular insights of carbapenem resistance Klebsiella pneumoniae isolates with focus on multidrug resistance from clinical samples
S Indrajith, AK Mukhopadhyay, G Chowdhury… - Journal of Infection and …, 2021 - Elsevier
Background Carbapenem are the last-line antibiotic, defence against Gram-negative
extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance …
extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance …
Recurrent emergence of Klebsiella pneumoniae carbapenem resistance mediated by an inhibitory ompK36 mRNA secondary structure
JLC Wong, S David… - Proceedings of the …, 2022 - National Acad Sciences
Outer membrane porins in Gram-negative bacteria facilitate antibiotic influx. In Klebsiella
pneumoniae, modifications in the porin OmpK36 are implicated in increasing resistance to …
pneumoniae, modifications in the porin OmpK36 are implicated in increasing resistance to …
Extensively drug-resistant Klebsiella pneumoniae counteracts fitness and virulence costs that accompanied ceftazidime-avibactam resistance acquisition
E Eger, M Schwabe, L Schulig, NO Hübner… - Microbiology …, 2022 - Am Soc Microbiol
The ability of extensively drug-resistant (XDR) Klebsiella pneumoniae to rapidly acquire
resistance to novel antibiotics is a global concern. Moreover, Klebsiella clonal lineages that …
resistance to novel antibiotics is a global concern. Moreover, Klebsiella clonal lineages that …