Mechanical properties of human tumour tissues and their implications for cancer development

A Massey, J Stewart, C Smith, C Parvini… - Nature Reviews …, 2024 - nature.com
The mechanical properties of cells and tissues help determine their architecture,
composition and function. Alterations to these properties are associated with many diseases …

Focal adhesion dynamics in cellular function and disease

YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

[HTML][HTML] Traction force microscopy–Measuring the forces exerted by cells

M Lekka, K Gnanachandran, A Kubiak, T Zieliński… - Micron, 2021 - Elsevier
Cells generate mechanical forces (traction forces, TFs) while interacting with the
extracellular matrix or neighbouring cells. Forces are generated by both cells and …

Role of internalin proteins in the pathogenesis of Listeria monocytogenes

K Ireton, R Mortuza, GC Gyanwali… - Molecular …, 2021 - Wiley Online Library
Listeria monocytogenes is a food‐borne bacterium that causes gastroenteritis, meningitis, or
abortion. L. monocytogenes induces its internalization (entry) into human cells and either …

A review on the recent progress, opportunities, and challenges of 4D printing and bioprinting in regenerative medicine

P Pourmasoumi, A Moghaddam… - Journal of …, 2023 - Taylor & Francis
Abstract Four-dimensional (4 D) printing is a novel emerging technology, which can be
defined as the ability of 3 D printed materials to change their form and functions. The term …

Integration of extracellular matrices into organ‐on‐chip systems

H Kutluk, EE Bastounis… - Advanced Healthcare …, 2023 - Wiley Online Library
The extracellular matrix (ECM) is a complex, dynamic network present within all tissues and
organs that not only acts as a mechanical support and anchorage point but can also direct …

A review of single-cell adhesion force kinetics and applications

A Shinde, K Illath, P Gupta, P Shinde, KT Lim, M Nagai… - Cells, 2021 - mdpi.com
Cells exert, sense, and respond to the different physical forces through diverse mechanisms
and translating them into biochemical signals. The adhesion of cells is crucial in various …

The complex interactions between the cellular and non-cellular components of the brain tumor microenvironmental landscape and their therapeutic implications

SM Faisal, A Comba, ML Varela, AE Argento… - Frontiers in …, 2022 - frontiersin.org
Glioblastoma (GBM), an aggressive high-grade glial tumor, is resistant to therapy and has a
poor prognosis due to its universal recurrence rate. GBM cells interact with the non-cellular …

Biophysical approaches for applying and measuring biological forces

W Sun, X Gao, H Lei, W Wang, Y Cao - Advanced Science, 2022 - Wiley Online Library
Over the past decades, increasing evidence has indicated that mechanical loads can
regulate the morphogenesis, proliferation, migration, and apoptosis of living cells …

FilamentSensor 2.0: An open-source modular toolbox for 2D/3D cytoskeletal filament tracking

L Hauke, A Primeßnig, B Eltzner, J Radwitz… - PLoS …, 2023 - journals.plos.org
Cytoskeletal pattern formation and structural dynamics are key to a variety of biological
functions and a detailed and quantitative analysis yields insight into finely tuned and well …