[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …
[HTML][HTML] Origin and evolution of pathogenic coronaviruses
J Cui, F Li, ZL Shi - Nature reviews microbiology, 2019 - nature.com
Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory
syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses …
syndrome coronavirus (MERS-CoV) are two highly transmissible and pathogenic viruses …
[HTML][HTML] A pneumonia outbreak associated with a new coronavirus of probable bat origin
Since the outbreak of severe acute respiratory syndrome (SARS) 18 years ago, a large
number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural …
number of SARS-related coronaviruses (SARSr-CoVs) have been discovered in their natural …
[HTML][HTML] A new coronavirus associated with human respiratory disease in China
F Wu, S Zhao, B Yu, YM Chen, W Wang, ZG Song… - Nature, 2020 - nature.com
Emerging infectious diseases, such as severe acute respiratory syndrome (SARS) and Zika
virus disease, present a major threat to public health 1, 2, 3. Despite intense research efforts …
virus disease, present a major threat to public health 1, 2, 3. Despite intense research efforts …
Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
Over the past 20 years, several coronaviruses have crossed the species barrier into
humans, causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV …
humans, causing outbreaks of severe, and often fatal, respiratory illness. Since SARS-CoV …
Structural and functional basis of SARS-CoV-2 entry by using human ACE2
The recent emergence of a novel coronavirus (SARS-CoV-2) in China has caused
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
[HTML][HTML] The origins of SARS-CoV-2: A critical review
Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus
in December 2019 in Wuhan, China, there has been intense interest in understanding how …
in December 2019 in Wuhan, China, there has been intense interest in understanding how …
[HTML][HTML] Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
Animal models for COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the aetiological agent of
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …
coronavirus disease 2019 (COVID-19), an emerging respiratory infection caused by the …
[HTML][HTML] SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract
The mode of acquisition and causes for the variable clinical spectrum of coronavirus disease
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …
2019 (COVID-19) remain unknown. We utilized a reverse genetics system to generate a …