A review of the clinical efficacy of FDA-approved antibody‒drug conjugates in human cancers

K Liu, M Li, Y Li, Y Li, Z Chen, Y Tang, M Yang… - Molecular Cancer, 2024 - Springer
While strategies such as chemotherapy and immunotherapy have become the first-line
standard therapies for patients with advanced or metastatic cancer, acquired resistance is …

Artificial intelligence in breast cancer diagnosis and personalized medicine

JS Ahn, S Shin, SA Yang, EK Park… - Journal of Breast …, 2023 - pmc.ncbi.nlm.nih.gov
Breast cancer is a significant cause of cancer-related mortality in women worldwide. Early
and precise diagnosis is crucial, and clinical outcomes can be markedly enhanced. The rise …

Tumor-infiltrating lymphocytes in triple-negative breast cancer

RA Leon-Ferre, SF Jonas, R Salgado, S Loi, V De Jong… - Jama, 2024 - jamanetwork.com
Importance The association of tumor-infiltrating lymphocyte (TIL) abundance in breast
cancer tissue with cancer recurrence and death in patients with early-stage triple-negative …

Liquid biopsy in cancer current: status, challenges and future prospects

L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024 - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Current treatment landscape for early triple-negative breast cancer (TNBC)

J Lee - Journal of clinical medicine, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) accounts for 15–20% of all breast cancers and is
characterized by an aggressive nature and a high rate of recurrence despite neoadjuvant …

HER2-targeted therapies in cancer: a systematic review

K Zhu, X Yang, H Tai, X Zhong, T Luo, H Zheng - Biomarker Research, 2024 - Springer
Abnormal alterations in human epidermal growth factor receptor 2 (HER2, neu, and erbB2)
are associated with the development of many tumors. It is currently a crucial treatment for …

The role of PET/CT in breast cancer

B Hadebe, L Harry, T Ebrahim, V Pillay, M Vorster - Diagnostics, 2023 - mdpi.com
Female breast cancer has surpassed lung cancer as the most commonly diagnosed cancer
worldwide, with an estimated 2.3 million new cases (11.7%), followed by lung cancer …

Postoperative radiotherapy omission in selected patients with early breast cancer following preoperative breast MRI (PROSPECT): primary results of a prospective two …

GB Mann, AR Skandarajah, N Zdenkowski, J Hughes… - The Lancet, 2024 - thelancet.com
Background Adjuvant breast radiotherapy as a standard component of breast-conserving
treatment for early cancer can overtreat many women. Breast MRI is the most sensitive …

[HTML][HTML] Estrogen deprivation effects of endocrine therapy in breast cancer patients: Incidence, management and outcome

L Cucciniello, G Garufi, R Di Rienzo, C Martinelli… - Cancer Treatment …, 2023 - Elsevier
Endocrine therapy is one of the standard adjuvant treatments to reduce the risk of
recurrence and mortality in patients with hormone receptor positive early breast cancer …

Safety of targeted axillary dissection after neoadjuvant therapy in patients with node-positive breast cancer

S Kuemmel, J Heil, S Bruzas, E Breit… - JAMA …, 2023 - jamanetwork.com
Importance The increasing use of neoadjuvant systemic therapy (NST) has led to substantial
pathological complete response rates in patients with initially node-positive, early breast …