Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
Recent advancements in the use of exosomes as drug delivery systems
EJ Bunggulawa, W Wang, T Yin, N Wang… - Journal of …, 2018 - Springer
Extracellular vesicles (EVs) are the substances that are released by most types of cells and
have an important role in cell to cell communication. Among the most highly researched EVs …
have an important role in cell to cell communication. Among the most highly researched EVs …
Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases
The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
Exosome-based vaccines: history, current state, and clinical trials
P Santos, F Almeida - Frontiers in immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular
communication system in crucial processes such as inflammation, cell proliferation, and …
communication system in crucial processes such as inflammation, cell proliferation, and …
[HTML][HTML] Circulating exosomes are strongly involved in SARS-CoV-2 infection
Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited,
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
hindering the understanding of COVID-19 pathogenesis and the development of therapeutic …
Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells
BH Sung, A von Lersner, J Guerrero… - Nature …, 2020 - nature.com
Small extracellular vesicles called exosomes affect multiple autocrine and paracrine cellular
phenotypes. Understanding the function of exosomes requires a variety of tools, including …
phenotypes. Understanding the function of exosomes requires a variety of tools, including …
The function and clinical application of extracellular vesicles in innate immune regulation
The innate immune system plays a crucial role in the host defense against viral and
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
microbial infection. Exosomes constitute a subset of extracellular vesicles (EVs) that can be …
Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications
Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …