Self-assembled monolayers of thiolates on metals as a form of nanotechnology

JC Love, LA Estroff, JK Kriebel, RG Nuzzo… - Chemical …, 2005 - ACS Publications
Nanoscience includes the study of objects and systems in which at least one dimension is 1-
100 nm. The objects studied in this range of sizes are larger than atoms and small …

Designing materials for biology and medicine

R Langer, DA Tirrell - Nature, 2004 - nature.com
Biomaterials have played an enormous role in the success of medical devices and drug
delivery systems. We discuss here new challenges and directions in biomaterials research …

Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

O Blixt, S Head, T Mondala… - Proceedings of the …, 2004 - National Acad Sciences
Here we describe a glycan microarray constructed by using standard robotic microarray
printing technology to couple amine functionalized glycans to an amino-reactive glass slide …

Protein nanoarrays generated by dip-pen nanolithography

KB Lee, SJ Park, CA Mirkin, JC Smith, M Mrksich - Science, 2002 - science.org
Dip-pen nanolithography was used to construct arrays of proteins with 100-to 350-
nanometer features. These nanoarrays exhibit almost no detectable nonspecific binding of …

Protein chip technology

H Zhu, M Snyder - Current opinion in chemical biology, 2003 - Elsevier
Microarray technology has become a crucial tool for large-scale and high-throughput
biology. It allows fast, easy and parallel detection of thousands of addressable elements in a …

Diels–Alder “click” reactions: recent applications in polymer and material science

MA Tasdelen - Polymer Chemistry, 2011 - pubs.rsc.org
The “click” chemistry concept is based on utilizing rapid reactions which are efficient,
versatile, and selective. Indeed, Diels–Alder (DA) reactions fulfill most of the requirements …

Synthesis and medical applications of oligosaccharides

PH Seeberger, DB Werz - Nature, 2007 - nature.com
Our understanding of the different glycoconjugates present on cells, proteins and entire
organisms is lagging far behind advances in genomics and proteomics. Carbohydrate …

“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates

SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …

An extracellular matrix microarray for probing cellular differentiation

CJ Flaim, S Chien, SN Bhatia - Nature methods, 2005 - nature.com
We present an extracellular matrix (ECM) microarray platform for the culture of patterned
cells atop combinatorial matrix mixtures. This platform enables the study of differentiation in …

The molecular level modification of surfaces: from self-assembled monolayers to complex molecular assemblies

JJ Gooding, S Ciampi - Chemical Society Reviews, 2011 - pubs.rsc.org
The modification of surfaces with self-assembled monolayers (SAMs) containing multiple
different molecules, or containing molecules with multiple different functional components, or …