Trends and targets in antiviral phototherapy

A Wiehe, JM O'Brien, MO Senge - Photochemical & Photobiological …, 2019 - pubs.rsc.org
Photodynamic therapy (PDT) is a well-established treatment option in the treatment of
certain cancerous and pre-cancerous lesions. Though best-known for its application in …

[HTML][HTML] Molecular proteomics and signalling of human platelets in health and disease

J Huang, P Zhang, FA Solari, A Sickmann… - International Journal of …, 2021 - mdpi.com
Platelets are small anucleate blood cells that play vital roles in haemostasis and thrombosis,
besides other physiological and pathophysiological processes. These roles are tightly …

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryocytes covering platelet functions

J Huang, F Swieringa, FA Solari, I Provenzale… - Scientific reports, 2021 - nature.com
Novel platelet and megakaryocyte transcriptome analysis allows prediction of the full or
theoretical proteome of a representative human platelet. Here, we integrated the established …

A contemporary view of platelet-rich plasma therapies: moving toward refined clinical protocols and precise indications

I Andia, N Maffulli - Regenerative medicine, 2018 - Taylor & Francis
The positive extensive clinical experience with platelet-rich plasma (PRP) in different
medical areas has prompted researchers to explore clinical opportunities for optimized PRP …

[HTML][HTML] Proteomics of human platelet lysates and insight from animal studies on platelet protein diffusion to hippocampus upon intranasal administration

NTN Le, CL Han, L Delila, O Nebie, HT Chien… - APL …, 2024 - pubs.aip.org
Human platelet lysates (HPLs) from allogeneic platelet concentrates (PCs) are biomaterials,
which are rich in various trophic factors, increasingly used in regenerative medicine and …

Impact of different pathogen reduction technologies on the biochemistry, function, and clinical effectiveness of platelet concentrates: An updated view during a …

G Escolar, M Diaz‐Ricart, J McCullough - Transfusion, 2022 - Wiley Online Library
Standard platelet concentrates (PCs) stored at 22° C have a limited shelf life of 5 days.
Because of the storage temperature, bacterial contamination of PCs can result in life …

[HTML][HTML] Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets

ST Yunga, AJ Gower, AR Melrose, MK Fitzgerald… - Journal of Thrombosis …, 2022 - Elsevier
Background Ex vivo assays of platelet function critically inform mechanistic and clinical
hematology studies, where effects of divergent blood processing methods on platelet …

Proteomic analysis of extracellular vesicles derived from platelet concentrates treated with Mirasol® identifies biomarkers of platelet storage lesion

L Hermida-Nogueira, MN Barrachina, I Izquierdo… - Journal of …, 2020 - Elsevier
In blood banks, platelets are stored until 7 days after a pathogen reduction technology (PRT)
treatment, Mirasol®(vitamin B 2 plus UVB light) in the present case. The storage time under …

Characterization of the Antibacterial Activity of an SiO2 Nanoparticular Coating to Prevent Bacterial Contamination in Blood Products

S Fonseca, MP Cayer, KMT Ahmmed… - Antibiotics, 2022 - mdpi.com
Technological innovations and quality control processes within blood supply organizations
have significantly improved blood safety for both donors and recipients. Nevertheless, the …

Proteomics: a tool to study platelet function

O Shevchuk, AJ Begonja, S Gambaryan… - International journal of …, 2021 - mdpi.com
Platelets are components of the blood that are highly reactive, and they quickly respond to
multiple physiological and pathophysiological processes. In the last decade, it became clear …