Most epidermal functions can be considered as protective, or more specifically, as defensive
in nature. Yet, the term “barrier function” is often used synonymously with only one such …

The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

Objective: Mechanisms underlying mucosal transmission of HIV-1 are incompletely
understood. We describe the anti-HIV-1 activity of human β-defensins (hBD), small cationic …

The oral cavity is a unique environment in which antimicrobial peptides play a key role in
maintaining health and may have future therapeutic applications. Present evidence …

A group of interesting molecules called defensins exhibit multiple functions but have been
primarily recognized to possess a broad spectrum of antimicrobial activities. Studies have …

Objectives: The primary aetiologic factor of periodontal disease is the bacterial biofilm. Gram‐
positive and Gram‐negative bacteria possess a plethora of structural or secreted …

Host defence peptides (HDPs) are short cationic molecules produced by the immune
systems of most multicellular organisms and play a central role as effector molecules of …

ABSTRACT Human β-defensins 2 and 3 (HBD-2 and HBD-3) are inducible peptides present
at sites of infection in the oral cavity. A few studies have reported broad-spectrum …

Oral epithelial barrier consists of closely controlled structure of the stratified squamous
epithelium, which is the gateway to human bodies and encounters a huge burden of …