Role of immunity and vaginal microbiome in clearance and persistence of human papillomavirus infection

L Ntuli, A Mtshali, G Mzobe, LJP Liebenberg… - Frontiers in cellular …, 2022 - frontiersin.org
Cervical cancer disproportionately affects women of reproductive age, with 80% of cases
occurring in low-and middle-income countries. Persistent infection with high-risk human …

Recent advances and methodological considerations on vaccine candidates for human schistosomiasis

U Panzner, JL Excler, JH Kim, F Marks… - Frontiers in Tropical …, 2021 - frontiersin.org
Schistosomiasis remains a neglected tropical disease of major public health concern with
high levels of morbidity in various parts of the world. Although considerable efforts in …

Non-covalent inhibitors of thioredoxin glutathione reductase with schistosomicidal activity in vivo

VZ Petukhova, SY Aboagye, M Ardini, RP Lullo… - Nature …, 2023 - nature.com
Only praziquantel is available for treating schistosomiasis, a disease affecting more than
200 million people. Praziquantel-resistant worms have been selected for in the lab and low …

Hydroxycarbamide treatment reduces transcranial Doppler velocity in the absence of transfusion support in children with sickle cell anaemia, elevated transcranial …

A Rankine‐Mullings, M Reid, D Soares… - British Journal of …, 2021 - Wiley Online Library
Summary EXpanding Treatment for Existing Neurological Disease (EXTEND) investigated
whether hydroxycarbamide lowers transcranial Doppler (TCD) velocities in Jamaican …

The role of dendritic cells in TB and HIV infection

R Abrahem, E Chiang, J Haquang, A Nham… - Journal of Clinical …, 2020 - mdpi.com
Dendritic cells are the principal antigen-presenting cells (APCs) in the host defense
mechanism. An altered dendritic cell response increases the risk of susceptibility of …

Prevalence of antibodies to Toxocara canis and its associated risk factors in socio‐economically deprived nomadic communities of Pakistan

MM Awais, S Zahoor, M Akhtar… - Zoonoses and Public …, 2023 - Wiley Online Library
Toxocariasis is an important zoonotic disease caused by Toxocara (T.) canis with
considerably higher prevalence in develo** countries. The data on its epidemiology …

Uncovering HIV and malaria interactions: the latest evidence and knowledge gaps

A Figueroa-Romero, A Saura-Lázaro… - The Lancet …, 2024 - thelancet.com
The geographical distribution of malaria and HIV infections widely overlap in sub-Saharan
Africa, constituting a complex global health challenge. The interplay between both infections …

Urinary bladder Schistosoma haematobium-related squamous cell carcinoma: a report of two fatal cases and literature review

B Efared, ABA Bako, B Idrissa, D Alhousseini… - … , Travel Medicine and …, 2022 - Springer
Background Schistosomiasis is still a public health issue in certain areas of develo**
countries (especially in sub-saharan Africa). Schistosoma haematobium is a proven …

The syndemic of substance use, high-risk sexual behavior, and violence: a qualitative exploration of the intersections and implications for HIV/STI prevention among …

O Dirisu, M Adediran, A Omole, A Akinola… - Frontiers in tropical …, 2022 - frontiersin.org
Background Key populations (KP) are defined groups with an increased risk of HIV due to
specific higher risk behaviours. KP who use substances engage in risky behaviors that may …

Narrative Review on Endemic Communicable Diseases in Africa: Mortality and Morbidity Trends, Impacts on Families, and the Way Forward

A Tartour, T Osman, R Javed, R Ali, A Syed… - Qatar Journal of Public …, 2024 - qscience.com
African nations have experienced various environmental and anthropological changes,
including climate change, natural disasters, food safety issues, and increased industrial …