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Statistical methods and resources for biomarker discovery using metabolomics
Metabolomics is a dynamic tool for elucidating biochemical changes in human health and
disease. Metabolic profiles provide a close insight into physiological states and are highly …
disease. Metabolic profiles provide a close insight into physiological states and are highly …
The interplay between obesity, immunosenescence, and insulin resistance
Obesity, which is the accumulation of fat in adipose tissue, has adverse impacts on human
health. Obesity-related metabolic dysregulation has similarities to the metabolic alterations …
health. Obesity-related metabolic dysregulation has similarities to the metabolic alterations …
Butyrate and obesity: Current research status and future prospect
K Peng, W Dong, T Luo, H Tang, W Zhu… - Frontiers in …, 2023 - frontiersin.org
Over the past few decades, increasing prevalence of obesity caused an enormous medical,
social, and economic burden. As the sixth most important risk factor contributing to the …
social, and economic burden. As the sixth most important risk factor contributing to the …
Diabetes remission after bariatric surgery
M Chumakova-Orin, C Vanetta, DP Moris… - World journal of …, 2021 - pmc.ncbi.nlm.nih.gov
Over the last decade, obesity rates have continued to rise in the United States as well as
worldwide and are showing no signs of slowing down. This rise is in parallel with the …
worldwide and are showing no signs of slowing down. This rise is in parallel with the …
EPA and DHA differentially improve insulin resistance by reducing adipose tissue inflammation—targeting GPR120/PPARγ pathway
X Yang, X Li, M Hu, J Huang, S Yu, H Zeng… - The Journal of nutritional …, 2024 - Elsevier
Insulin resistance (IR) is a global health challenge, often initiated by dysfunctional adipose
tissue. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may have different …
tissue. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may have different …
Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians
AP Doumatey, D Shriner, J Zhou, L Lei, G Chen… - Genome Medicine, 2024 - Springer
Abstract Background Type 2 diabetes (T2D) has reached epidemic proportions globally,
including in Africa. However, molecular studies to understand the pathophysiology of T2D …
including in Africa. However, molecular studies to understand the pathophysiology of T2D …
[HTML][HTML] Therapeutic effects of curcumin derivatives against obesity and associated metabolic complications: A review of in vitro and in vivo studies
MT Moetlediwa, R Ramashia, C Pheiffer… - International Journal of …, 2023 - mdpi.com
Obesity is a major cause of morbidity and mortality globally, increasing the risk for chronic
diseases. Thus, the need to identify more effective anti-obesity agents has spurred …
diseases. Thus, the need to identify more effective anti-obesity agents has spurred …
Characteristics of the intestinal flora in patients with peripheral neuropathy associated with type 2 diabetes
Y Wang, X Ye, D Ding, Y Lu - Journal of International …, 2020 - journals.sagepub.com
Objective To study the characteristics of the intestinal flora in patients with diabetic
peripheral neuropathy (DPN) and analyze the association between the intestinal flora and …
peripheral neuropathy (DPN) and analyze the association between the intestinal flora and …
[HTML][HTML] Therapeutic Potential of Various Intermittent Fasting Regimens in Alleviating Type 2 Diabetes Mellitus and Prediabetes: A Narrative Review
S Msane, A Khathi, A Sosibo - Nutrients, 2024 - mdpi.com
Intermittent fasting has drawn significant interest in the clinical research community due to its
potential to address metabolic complications such as obesity and type 2 diabetes mellitus …
potential to address metabolic complications such as obesity and type 2 diabetes mellitus …
Protective role of zinc in the pathogenesis of respiratory diseases
R Luan, D Ding, Q Xue, H Li, Y Wang… - European Journal of …, 2023 - nature.com
Respiratory diseases remain a major cause of morbidity and mortality worldwide. An
imbalance of zinc, an essential trace element, is associated with a variety of lung diseases …
imbalance of zinc, an essential trace element, is associated with a variety of lung diseases …