Objective Social isolation and loneliness are associated with poor health (immunity,
inflammation, etc.) in ageing. The purpose of this sco** review was to investigate the link …

The current literature provides a body of evidence on C-Reactive Protein (CRP) and its
potential role in inflammation. However, most pieces of evidence are sparse and …

Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …

Chronic low-grade inflammation is linked to a multitude of chronic diseases. We report the
largest genome-wide association study (GWAS) on C-reactive protein (CRP), a marker of …

Background Although observational studies have reported associations between serum C-
reactive protein (CRP) concentration and risks of lung, breast, and colorectal cancer …

With the growing number of genetic association studies, the genotype-phenotype atlas has
become increasingly more complex, yet the functional consequences of most disease …

The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

Objective: The authors investigated the pathways (genetic, environmental, lifestyle, medical)
leading to inflammation in major depressive disorder using C-reactive protein (CRP) …

Mendelian randomisation (MR) analysis is an important tool to elucidate the causal
relevance of environmental and biological risk factors for disease. However, causal …

Background: Clonal hematopoiesis of indeterminate potential (CHIP) refers to clonal
expansion of hematopoietic stem cells attributable to acquired leukemic mutations in genes …