Immunosenescence in atherosclerosis: A role for chronic viral infections

A Ghamar Talepoor, M Doroudchi - Frontiers in immunology, 2022‏ - frontiersin.org
Immune system is a versatile and dynamic body organ which offers survival and endurance
of human beings in their hostile living environment. However, similar to other cells, immune …

Noncoding RNAs in cardiovascular disease: pathological relevance and emerging role as biomarkers and therapeutics

RS Gangwar, S Rajagopalan… - American journal of …, 2018‏ - academic.oup.com
Noncoding RNAs (ncRNA) include a diverse range of functional RNA species—microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs) being most studied in pathophysiology …

The miR‐126‐5p and miR‐212‐3p in the extracellular vesicles activate monocytes in the early stage of radiation‐induced vascular inflammation implicated in …

YY Choi, A Kim, Y Lee, YH Lee, M Park… - Journal of …, 2023‏ - Wiley Online Library
People exposed to radiation in cancer therapy and nuclear accidents are at increased risk of
cardiovascular outcomes in long‐term survivors. Extracellular vesicles (EVs) are involved in …

Exosomes derived from senescent endothelial cells contain distinct pro-angiogenic miRNAs and proteins

SA Shaban, J Rezaie, V Nejati - Cardiovascular toxicology, 2022‏ - Springer
Exosomes from senescence cells play pivotal roles in endothelium dysfunction. We
investigated the exosomal angiogenic cargo of endothelial cells (ECs) in a model of …

Overexpression of microRNA-21-5p and microRNA-221-5p in Monocytes Increases the Risk of Develo** Coronary Artery Disease

YE Torres-Paz, R Gamboa… - International Journal of …, 2023‏ - mdpi.com
MicroRNAs (miRs) regulate gene expression at the post-transcriptional level and are found
to be present in monocytes. This study aimed to investigate miR-221-5p, miR-21-5p, and …

The pro-angiogenesis effect of miR33a-5p/Ets-1/DKK1 signaling in ox-LDL induced HUVECs

M Di, Y Zhang, R Zeng, X Liu, W Chen… - International …, 2021‏ - pmc.ncbi.nlm.nih.gov
Objective: Angiogenesis is involved in multiple biological processes, including
atherosclerosis (AS) and cancer. Dickkopf1 (DKK1) plays many roles in both tumors and AS …

Increased expression of resistin in microRNA-155-deficient white adipose tissues may be a possible driver of metabolically healthy obesity transition to classical …

C Johnson, C Drummer IV, A Virtue, T Gao… - Frontiers in …, 2018‏ - frontiersin.org
We reported that microRNA-155 (miR-155) deficiency in ApoE-/-mice yields a novel
metabolically healthy obese (MHO) model, which exhibits improved atherosclerosis but …

Differential effect of intermittent hypoxia and sleep fragmentation on PD-1/PD-L1 upregulation

C Cubillos-Zapata, I Almendros, E Díaz-García… - Sleep, 2020‏ - academic.oup.com
Immunosurveillance is compromised in patients with obstructive sleep apnea (OSA) as
reflected by overexpression of the programmed death cell receptor and its ligand (PD-1/PD …

The essence of lipoproteins in cardiovascular health and diseases treated by photodynamic therapy

P Wańczura, D Aebisher, MA Iwański, A Myśliwiec… - Biomedicines, 2024‏ - mdpi.com
Lipids, together with lipoprotein particles, are the cause of atherosclerosis, which is a
pathology of the cardiovascular system. In addition, it affects inflammatory processes and …

Interactions among regulatory non-coding RNAs involved in cardiovascular diseases

AF Gabriel, MC Costa, FJ Enguita - Non-coding RNAs in Cardiovascular …, 2020‏ - Springer
Non-coding RNAs (ncRNAs) are important regulatory players in human cells that have been
shown to modulate different cellular processes and biological functions through controlling …