Recent advances in the use of microfluidic technologies for single cell analysis
The inherent heterogeneity in cell populations has become of great interest and importance
as analytical techniques have improved over the past decades. With the advent of …
as analytical techniques have improved over the past decades. With the advent of …
Microfluidics for manipulating cells
Microfluidics, a toolbox comprising methods for precise manipulation of fluids at small length
scales (micrometers to millimeters), has become useful for manipulating cells. Its uses range …
scales (micrometers to millimeters), has become useful for manipulating cells. Its uses range …
Highly efficient capture of circulating tumor cells by using nanostructured silicon substrates with integrated chaotic micromixers
Metastases are the most common cause of cancer-related death in patients with solid
tumors.[1–4] A considerable body of evidence indicates that tumor cells are shed from a …
tumors.[1–4] A considerable body of evidence indicates that tumor cells are shed from a …
The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation
The generation of research-quality, clinically relevant cell types in vitro from human
pluripotent stem cells requires a detailed understanding of the equivalent human cell types …
pluripotent stem cells requires a detailed understanding of the equivalent human cell types …
NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells
Circulating tumor cells (CTCs) are cancer cells shredded from either a primary tumor or a
metastatic site and circulate in the blood as the potential cellular origin of metastasis. By …
metastatic site and circulate in the blood as the potential cellular origin of metastasis. By …
Microfluidics towards single cell resolution protein analysis
Single cell analysis has aroused great interest with its remarkable ability to investigate cell-
to-cell heterogeneity in large populations. However, probing protein information at single …
to-cell heterogeneity in large populations. However, probing protein information at single …
Review of methods to probe single cell metabolism and bioenergetics
Single cell investigations have enabled unexpected discoveries, such as the existence of
biological noise and phenotypic switching in infection, metabolism and treatment. Herein …
biological noise and phenotypic switching in infection, metabolism and treatment. Herein …
Rapid microfluidic formation of uniform patient-derived breast tumor spheroids
Breast cancer is a highly complex, heterogeneous, and multifactorial disease that poses
challenges for rapid and efficient treatment and development of personalized therapy. Here …
challenges for rapid and efficient treatment and development of personalized therapy. Here …
Induction of human iPSC-derived cardiomyocyte proliferation revealed by combinatorial screening in high density microbioreactor arrays
Inducing cardiomyocyte proliferation in post-mitotic adult heart tissue is attracting significant
attention as a therapeutic strategy to regenerate the heart after injury. Model animal screens …
attention as a therapeutic strategy to regenerate the heart after injury. Model animal screens …
Scaling up stem cell production: harnessing the potential of microfluidic devices
Stem cells are specialised cells characterised by their unique ability to both self-renew and
transform into a wide array of specialised cell types. The widespread interest in stem cells for …
transform into a wide array of specialised cell types. The widespread interest in stem cells for …