α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition

DM Perez - Frontiers in pharmacology, 2020 - frontiersin.org
α1-adrenergic receptors are G-Protein Coupled Receptors that are involved in
neurotransmission and regulate the sympathetic nervous system through binding and …

Correlation between ferumoxytol uptake in tumor lesions by MRI and response to nanoliposomal irinotecan in patients with advanced solid tumors: a pilot study

RK Ramanathan, RL Korn, N Raghunand… - Clinical Cancer …, 2017 - aacrjournals.org
Purpose: To determine whether deposition characteristics of ferumoxytol (FMX) iron
nanoparticles in tumors, identified by quantitative MRI, may predict tumor lesion response to …

How to stop using gadolinium chelates for magnetic resonance imaging: clinical-translational experiences with ferumoxytol

HE Daldrup-Link, AJ Theruvath, A Rashidi, M Iv… - Pediatric …, 2022 - Springer
Gadolinium chelates have been used as standard contrast agents for clinical MRI for several
decades. However, several investigators recently reported that rare Earth metals such as …

[HTML][HTML] Cognitive impairment, sleep disturbance, and depression in women with silicone breast implants: association with autoantibodies against autonomic nervous …

M Tocut, G Halpert, AM Tsur, K Sharif, H Heidecke… - Biomolecules, 2022 - mdpi.com
Background: Silicone breast implants (SBIs) has been shown to be associated with an
increased risk of autoimmune diseases. In the current study, we aimed to explore the …

Inhibiting α1‐adrenergic receptor signaling pathway ameliorates AD‐type pathologies and behavioral deficits in APPswe/PS1 mouse model

ZY Yu, X Yi, YR Wang, GH Zeng, CR Tan… - Journal of …, 2022 - Wiley Online Library
The role of α1 adrenergic receptors (α1‐ARs) signaling pathway in the pathogenesis of
Alzheimer's disease (AD) has rarely been investigated. Clarifying the pathophysiological …

Pretherapy ferumoxytol-enhanced MRI to predict response to liposomal irinotecan in metastatic breast cancer

H Ravi, AM Arias-Lorza, JR Costello, HS Han… - Radiology: Imaging …, 2023 - pubs.rsna.org
Purpose To investigate ferumoxytol (FMX)-enhanced MRI as a pretreatment predictor of
response to liposomal irinotecan (nal-IRI) for thoracoabdominal and brain metastases in …

[PDF][PDF] Role of alpha1-adrenergic receptor antibodies in Alzheimer's disease

P Karczewski, P Hempel, M Bimmler - Front. Biosci, 2018 - article.imrpress.com
2082 Role of alpha1-adrenergic receptor antibodies in Alzheimer‘s disease Peter
Karczewski1, Petra Hempel1, Marion Bimmler1 1 Page 1 2082 Role of alpha1-adrenergic …

Experimental MRI monitoring of renal blood volume fraction variations en route to renal magnetic resonance oximetry

A Pohlmann, K Cantow, T Huelnhagen… - …, 2017 - pmc.ncbi.nlm.nih.gov
Diagnosis of early-stage acute kidney injury (AKI) will benefit from a timely identification of
local tissue hypoxia. Renal tissue hypoxia is an early feature in AKI pathophysiology, and …

[HTML][HTML] Deciphering the Role of Adrenergic Receptors in Alzheimer's Disease: Paving the Way for Innovative Therapies

AN Miliotou, A Kotsoni, LC Zacharia - Biomolecules, 2025 - mdpi.com
Neurodegenerative diseases are currently among the most devastating diseases with no
effective disease-modifying drugs in the market, with Alzheimer's disease (AD) being the …

Immunoadsorption of Agonistic Autoantibodies Against α1‐Adrenergic Receptors in Patients With Mild to Moderate Dementia

P Hempel, B Heinig, C Jerosch, I Decius… - Therapeutic …, 2016 - Wiley Online Library
Dementia has been shown to be associated with agonistic autoantibodies. The deleterious
action of autoantibodies on the α1‐adrenergic receptor for brain vasculature has been …