Ischemic stroke is one of the major causes of morbidity and mortality, affecting millions of
people worldwide. Inevitably, the interruption of cerebral blood supply after ischemia may …

Cerebral ischemia–reperfusion injury (CI/RI) injury is a common feature of ischemic stroke
which occurs when the blood supply is restored after a period of ischemia in the brain …

Background Perioperative neurocognitive disorders (PND) with a high incidence frequently
occur in elderly surgical patients closely associated with prolonged anesthesia-induced …

The latest research indicates that modulating microglial polarization from M1 to M2
phenotype may be a co** therapy for ischemic stroke. The present study thereby …

Background The pathogenesis of post-stroke depression (PSD) remains largely unknown.
There is growing evidence indicating that gut microbiota participates in the development of …

Augmentation of endoplasmic reticulum (ER) stress may trigger excessive oxidative stress,
which induces mitochondrial dysfunction. The fatty acid amide hydrolase inhibitor, URB597 …

Ischemic stroke is an acute cerebrovascular disease characterized by high mortality,
morbidity and disability rates. Ischemia/reperfusion is a critical pathophysiological basis of …

Acute cerebral ischaemia may lead to serious consequences, including brain injury caused
by uncontrolled reperfusion, which occurs when circulation is re-established. The long non …

Objective This review discusses recent experimental and clinical findings related to
ferroptosis, with a focus on the role of MSCs. Therapeutic efficacy and current applications of …

Post-stroke depression (PSD) is the most common mental disorder in stroke survivors.
However, its specific pathophysiology remains largely unknown. Previous studies suggested …