The role of dorsal raphe nucleus serotonergic and non-serotonergic neurons, and of their receptors, in regulating waking and rapid eye movement (REM) sleep
JM Monti - Sleep medicine reviews, 2010 - Elsevier
Based on electrophysiological, neurochemical, genetic and neuropharmacological
approaches it is currently accepted that serotonin (5-HT) functions to promote waking (W) …
approaches it is currently accepted that serotonin (5-HT) functions to promote waking (W) …
Raphe serotonin neurons are not homogenous: electrophysiological, morphological and neurochemical evidence
LH Calizo, A Akanwa, X Ma, Y Pan, JC Lemos… - …, 2011 - Elsevier
The median (MR) and dorsal raphe (DR) nuclei contain the majority of the 5-
hydroxytryptamine (5-HT, serotonin) neurons that project to limbic forebrain regions, are …
hydroxytryptamine (5-HT, serotonin) neurons that project to limbic forebrain regions, are …
Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety
JW Richardson-Jones, CP Craige… - Journal of …, 2011 - Soc Neuroscience
Identifying the factors contributing to the etiology of anxiety and depression is critical for the
development of more efficacious therapies. Serotonin (5-HT) is intimately linked to both …
development of more efficacious therapies. Serotonin (5-HT) is intimately linked to both …
HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience
J Espallergues, SL Teegarden… - Journal of …, 2012 - Soc Neuroscience
Genetic variations in certain components of the glucocorticoid receptor (GR) chaperone
complex have been associated with the development of stress-related affective disorders …
complex have been associated with the development of stress-related affective disorders …
Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids
SD Geddes, S Assadzada, D Lemelin… - Proceedings of the …, 2016 - National Acad Sciences
Serotonin (5-HT) neurons located in the raphe nuclei modulate a wide range of behaviors by
means of an expansive innervation pattern. In turn, the raphe receives a vast array of …
means of an expansive innervation pattern. In turn, the raphe receives a vast array of …
Classical neurotransmitters and neuropeptides involved in major depression: a review
FM Werner, R Covenas - International Journal of Neuroscience, 2010 - Taylor & Francis
We propose several pathways that could be involved in major depression. According to our
proposal, noradrenaline hypoactivity could occur through a strong presynaptic GABAergic …
proposal, noradrenaline hypoactivity could occur through a strong presynaptic GABAergic …
Which clinical and experimental data link temporal lobe epilepsy with depression?
D Kondziella, S Alvestad, A Vaaler… - Journal of …, 2007 - Wiley Online Library
The association of temporal lobe epilepsy with depression and other neuropsychiatric
disorders has been known since the early beginnings of neurology and psychiatry …
disorders has been known since the early beginnings of neurology and psychiatry …
GABAergic modulation of serotonergic neurons in the dorsal raphe nucleus
F Hernández-Vázquez, J Garduño… - Reviews in the …, 2019 - degruyter.com
The dorsal raphe nucleus (DRN), located in the brainstem, is involved in several functions
such as sleep, temperature regulation, stress responses, and anxiety behaviors. This …
such as sleep, temperature regulation, stress responses, and anxiety behaviors. This …
Increased intrinsic excitability of lateral wing serotonin neurons of the dorsal raphe: a mechanism for selective activation in stress circuits
LTK Crawford, CP Craige… - Journal of …, 2010 - journals.physiology.org
The primary center of serotonin (5-HT) projections to the forebrain is the dorsal raphe
nucleus (DR), a region known for its role in the limbic stress response. The ventromedial …
nucleus (DR), a region known for its role in the limbic stress response. The ventromedial …