Clinical epigenetics settings for cancer and cardiovascular diseases: real-life applications of network medicine at the bedside

F Sarno, G Benincasa, M List, AL Barabasi… - Clinical …, 2021 - Springer
Despite impressive efforts invested in epigenetic research in the last 50 years, clinical
applications are still lacking. Only a few university hospital centers currently use epigenetic …

Gene–environment interaction: A variable selection perspective

F Zhou, J Ren, X Lu, S Ma, C Wu - Epistasis: Methods and Protocols, 2021 - Springer
Gene–environment interactions have important implications for elucidating the genetic basis
of complex diseases beyond the joint function of multiple genetic factors and their …

TGPred: efficient methods for predicting target genes of a transcription factor by integrating statistics, machine learning and optimization

X Cao, L Zhang, MK Islam, M Zhao, C He… - NAR genomics and …, 2023 - academic.oup.com
Four statistical selection methods for inferring transcription factor (TF)–target gene (TG) pairs
were developed by coupling mean squared error (MSE) or Huber loss function, with elastic …

Gene selection by incorporating genetic networks into case-control association studies

X Cao, X Liang, S Zhang, Q Sha - European Journal of Human Genetics, 2024 - nature.com
Large-scale genome-wide association studies (GWAS) have been successfully applied to a
wide range of genetic variants underlying complex diseases. The network-based regression …

Sparse principal component analysis based on genome network for correcting cell type heterogeneity in epigenome-wide association studies

R Miao, Q Dang, J Cai, HH Huang, SL **e… - Medical & Biological …, 2022 - Springer
In epigenome-wide association studies (EWAS), the mixed methylation expression caused
by the combination of different cell types may lead the researchers to find the false …

Statistical methods for gene selection and genetic association studies

X Cao - 2023 - search.proquest.com
Michigan Tech Dissertation Template Page 1 STATISTICAL METHODS FOR GENE SELECTION
AND GENETIC ASSOCIATION STUDIES By Xuewei Cao A DISSERTATION Submitted in partial …

The Impact of School Social Experiences on Socioemotional and Behavioral Problems: The Hypothesized Role of DNA Methylation

M Comtois-Cabana, JM Buil, N Provençal… - … Toward Maladaptation in …, 2022 - Springer
Peer victimization (including physical, verbal, and relational forms of aggression) has a
worldwide prevalence rate of nearly 13%, and has been implicated in prior literature and …