Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Background The glucagon-like peptide-1 (GLP-1) is a multifaceted hormone with broad
pharmacological potential. Among the numerous metabolic effects of GLP-1 are the glucose …

Importance A major concern with weight loss is concomitant bone loss. Exercise and
glucagon-like peptide-1 receptor agonists (GLP-1RAs) represent weight loss strategies that …

Incretin hormones are gut peptides that are secreted after nutrient intake and stimulate
insulin secretion together with hyperglycaemia. GIP (glucose‐dependent insulinotropic …

The risk of fragility fractures is increased in patients with either type 1 diabetes mellitus
(T1DM) or type 2 diabetes mellitus (T2DM). Although BMD is decreased in T1DM, BMD in …

Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …

There is substantial, and growing, evidence that type 2 diabetes (T2D) is associated with
skeletal fragility, despite often preserved bone mineral density. As post-fracture outcomes …

Context Both type 2 diabetes (T2D) and osteoporosis are affected by aging and quite often
coexist. Furthermore, the fracture risk in patients with T2D is increased. The aim of this article …

The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide, especially as a
result of our aging society, high caloric intake and sedentary lifestyle. Besides the well …

Abstract Type 2 diabetes (T2 DM) is a rapidly growing public health problem. It is associated
with an increased risk of fracture, particularly of the hip, despite normal or high bone mineral …