[HTML][HTML] Hydrophilic interaction chromatography–mass spectrometry for metabolomics and proteomics: state-of-the-art and current trends

I Kohler, M Verhoeven, R Haselberg… - Microchemical Journal, 2022 - Elsevier
Among all the–omics approaches, proteomics and metabolomics have received increased
attention over the last decade. Both approaches have reached a certain level of maturity …

Qualitative and Quantitative Analytical Techniques of Nucleic Acid Modification Based on Mass Spectrometry for Biomarker Discovery

Y Liu, JH Dong, XY Shen, YX Gu, RH Zhang… - International Journal of …, 2024 - mdpi.com
Nucleic acid modifications play important roles in biological activities and disease
occurrences, and have been considered as cancer biomarkers. Due to the relatively low …

[HTML][HTML] Reverse phase, ion exchange, HILIC and mix-mode chromatography for the determination of metformin and evogliptin in human plasma and pharmaceutical …

PM Kharabe, PP Jumade, PN Khatale, PP Katolkar… - Talanta Open, 2024 - Elsevier
Separation and quantification of highly polar metformin (MTF) alone or in combination with
dipeptidyl peptidase-4 inhibitors, such as evogliptin (EVG), sitagliptin, saxagliptin …

A novel one-pot fluorescence tagging and depyrimidination strategy for quantification of global DNA methylation

X Liao, X Bai, S Wang, C Liggins, L Pan, M Wang… - Analytica chimica …, 2023 - Elsevier
DNA methylation is intensively studied in medical science. Current HPLC methods for
quantification of global DNA methylation involve digestion of a DNA sample and HPLC …

An on-line SPE-LC-MS/MS method for quantification of nucleobases and nucleosides present in biological fluids

YM Liu, S Wang, A Dickenson, J Mao, X Bai… - Analytical Methods, 2024 - pubs.rsc.org
Solid phase extraction (SPE) and liquid chromatographic (LC) separation of nucleobases
and nucleosides are challenging due to the high hydrophilicity of these compounds. Herein …

Protocol to compare column performance applied to hydrophilic interaction liquid chromatography

R Burgos-Gil, E Peris-Garcia, MJ Ruiz-Angel… - Microchemical …, 2019 - Elsevier
The lack of retention of highly polar solutes in liquid chromatography with reversed phase
columns (RPLC) can be solved through the use of the hydrophilic interaction liquid …

A relative quantitation method for measuring DNA methylation and hydroxymethylation using guanine as an internal standard

K Németh, K Mészáros, B Szabó, H Butz, T Arányi… - Analytical …, 2021 - pubs.rsc.org
Global DNA methylation and hydroxymethylation play an important role in gene expression.
They can be connected with several diseases. The modification status could be a biomarker …

[PDF][PDF] 质谱法定量生态物种基因组 DNA 低甲基化

胡俊杰, 吴毅聪, 陈桂连, 高圆圆, 赵桐, 余广… - **环境科学, 2022 - zghjkx.com.cn
为了定量生态相关物种基因组中低丰度的5-甲基-2-脱氧胞苷(5-mdC), 建立了一种采用高效液相
色谱串联质谱(HPLC-MS/MS) 的无标记方法. 全基因组DNA 甲基化计算公式5-mdC (mole)/(5 …

[PDF][PDF] Talanta Open

PM Kharabe, PP Jumade, PN Khatale, PP Katolkar… - researchgate.net
Separation and quantification of highly polar metformin (MTF) alone or in combination with
dipeptidyl peptidase-4 inhibitors, such as evogliptin (EVG), sitagliptin, saxagliptin …

Genomic analysis elucidating celluloysis of chemical enhanced primary sludge in anaerobic digestion toward crabon neutral sewage treatment in Hong Kong

H Zhuang - 2021 - theses.lib.polyu.edu.hk
This dissertation investigated the important anaerobic digestion (AD) treating high cellulose
content (30%) municipal sewage sludge produced after chemical enhanced primary …