Most molecular and cellular studies of cognitive function have focused on either normal or
pathological states, but recent research with transgenic mice has started to address the …

Since the first discovery of Kvβ-subunits more than 15 years ago, many more ancillary Kv
channel subunits were characterized, for example, KChIPs, KCNEs, and BKβ-subunits. The …

The mechanisms that determine how information is allocated to specific regions and cells in
the brain are important for memory capacity, storage and retrieval, but are poorly …

Experience-dependent changes in the structure of dendritic spines may contribute to
learning and memory. Encoded by three genes, the Shank family of postsynaptic scaffold …

Objective Decline in cognitive functions, including impaired acquisition of novel skills, is a
feature of older age that impacts activities of daily living, independence, and integration in …

The nervous system receives a large amount of information about the environment through
elaborate sensory routes. Processing and integration of these wide‐ranging inputs often …

Rapidly activating and inactivating cardiac transient outward K+ currents, Ito, are expressed
in most mammalian cardiomyocytes, and contribute importantly to the early phase of action …

Synaptic plasticity in the mammalian central nervous system has been the subject of intense
investigation for the past four decades. Long-term potentiation (LTP), a major reflection of …

Abstract “Use it or lose it” is a popular adage often associated with use-dependent
enhancement of cognitive abilities. Much research has focused on understanding exactly …

Background Cognitive, and motor performance are reduced in aging, especially with respect
to acquisition of new knowledge, which is associated with a neural plasticity decline. Animal …