Ligation technologies for the synthesis of cyclic peptides
Cyclic peptides have been attracting a lot of attention in recent decades, especially in the
area of drug discovery, as more and more naturally occurring cyclic peptides with diverse …
area of drug discovery, as more and more naturally occurring cyclic peptides with diverse …
Organophotocatalytic N–O Bond Cleavage of Weinreb Amides: Mechanism-Guided Evolution of a PET to ConPET Platform
A mild, organophotocatalytic N–O bond cleavage of Weinreb amides is disclosed, thereby
expanding the chemistry of this venerable motif beyond acylation. This redox neutral …
expanding the chemistry of this venerable motif beyond acylation. This redox neutral …
Catalytic asymmetric aza-Michael addition of fumaric monoacids with multifunctional thiourea/boronic acids
K Michigami, H Murakami, T Nakamura… - Organic & …, 2019 - pubs.rsc.org
The first chemical enantioselective synthesis of N-hydroxyaspartic acid derivatives using
chiral multifunctional thiourea/boronic acid organocatalysts was developed. A series of …
chiral multifunctional thiourea/boronic acid organocatalysts was developed. A series of …