Ligation technologies for the synthesis of cyclic peptides

HY Chow, Y Zhang, E Matheson, X Li - Chemical Reviews, 2019 - ACS Publications
Cyclic peptides have been attracting a lot of attention in recent decades, especially in the
area of drug discovery, as more and more naturally occurring cyclic peptides with diverse …

Organophotocatalytic N–O Bond Cleavage of Weinreb Amides: Mechanism-Guided Evolution of a PET to ConPET Platform

J Soika, C McLaughlin, T Neveselý, CG Daniliuc… - ACS …, 2022 - ACS Publications
A mild, organophotocatalytic N–O bond cleavage of Weinreb amides is disclosed, thereby
expanding the chemistry of this venerable motif beyond acylation. This redox neutral …

Catalytic asymmetric aza-Michael addition of fumaric monoacids with multifunctional thiourea/boronic acids

K Michigami, H Murakami, T Nakamura… - Organic & …, 2019 - pubs.rsc.org
The first chemical enantioselective synthesis of N-hydroxyaspartic acid derivatives using
chiral multifunctional thiourea/boronic acid organocatalysts was developed. A series of …